dibucaine


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dibucaine

 [di´bu-kān]
a potent local anesthetic applied rectally or topically to the anorectal region for treatment of hemorrhoids and other anorectal disorders, and topically to the skin in the treatment of minor skin disorders.

di·bu·caine

(dib'yū-kān),
A potent local anesthetic with a long duration of action used by injection or topically on skin or mucous membranes.

dibucaine

/di·bu·caine/ (di´bu-kān) a local anesthetic used topically on the skin and mucous membranes and rectally.

dibucaine

[dī′bəkān]
a topical anesthetic ointment often used to treat pain and itch of hemorrhoids.

di·bu·caine

(dib'yū-kān)
A potent local anesthetic with a long duration of action used by injection or topically on skin or mucous membranes.

di·bu·caine

(dib'yū-kān)
Potent local anesthetic with long action used by injection or topically on skin or mucous membranes.

dibucaine

a long-acting local anesthetic used topically and intraspinally in the form of the base and as the hydrochloride salt; the latter is also used intramuscularly for infiltration anesthesia. Called also cinchocaine. Has a special characteristic of needing only a small dose (about one-fortieth the dose of procaine).
References in periodicals archive ?
DIRECT DNA SEQUENCING FOR DIBUCAINE AND SIL-1 MUTATION ANALYSIS
The dibucaine and sil-1 mutations were analyzed by DNA sequencing because their relative proximity enabled them to be coamplified in a single 570-bp product.
In the 52 patients with hereditary hypocholinesterasemia, the most common DNA abnormalities were dibucaine and K-variant mutations: 47 patients carried the dibucaine mutation, whereas 48 were identified with the K-variant (allele frequencies, 0.
No homozygotes with fluoride or silent mutations were found, and none of the patients had an isolated homozygous dibucaine defect.
In total, 73% of patients with primary hypocholinesterasemia had abnormalities at the dibucaine and K-variant loci only.
This proband was heterozygous for dibucaine and K-variant, hence, compound heterozygous for three mutations (Fig.
Three patients had hypocholinesterasemia with BCHE gene defects: two K-variant homozygotes (patients 6 and 21), and one dibucaine heterozygote (patient 4; shown in the Data Supplement).
The importance of the dibucaine mutation in patients with primary hypocholinesterasemia was undisputable.
The mutation relationship responsible for most compound genotypes was coexpression of dibucaine and K-variant (88% of patients).
4) Nonstandard abbreviations: BCHE, butyrylcholine esterase; DN, dibucaine number; FN, fluoride number; SSCP, single-strand conformation polymorphism; and RFLP, restriction fragment length polymorphism.