diaminopyrimidines

diaminopyrimidines

Drugs used to treat or prevent MALARIA. Examples are pyrimethamine (Daraprim) and sulphadoxine with pyrimethamine (Fansidar).
References in periodicals archive ?
So, substituted 2,4 diaminopyrimidines are widely employed as metabolic inhibitors of pathways leading to the synthesis of proteins and nucleic acids [1].
Sulfonamides are also often used in combination with diaminopyrimidines (trimethoprim).
Electrochemical study of the kinetics of NADH being oxidized by diimines derived from diaminobenzenes and diaminopyrimidines. Journal of the American Chemical Society, v.
These drugs were administered alone from the 1930s through the 1960s in humans and were almost exclusively combined with diaminopyrimidines (e.g., trimethoprim) since the 1970s.
The next describes classes of agents and includes chapters on beta-lactam antibiotics; peptide antibiotics; lincosamides, pleuromutilins, and streptogramins; macrolides, azalides, and ketolides; aminoglycosides; tetracyclines and glycylcyclines; chloramphenicol, thiamphenicol, and florfenicol; sulfomanides, diaminopyrimidines, and their combinations; fluorquinolones; antifungal chemotherapy agents; and antiviral chemotherapy agents.
Savall B., y otros 8 autores, Diaminopyrimidines, diaminopyridines and diaminopyridazines as histamine H4 receptor modulators, doi: 10.1016/j.bmcl.2014.12.027, Bioorg.
Islam, "Iclaprim, a novel diaminopyrimidine with potent activity on trimethoprim sensitive and resistant bacteria," Bioorganic and Medicinal Chemistry Letters, vol.