For management of mild or suspected cases of bacterial conjunctivitis or blepharoconjunctivitis, diamidine
treatment is appropriate as an initial measure.
(18) Pentamidine, an aromatic diamidine
used in the treatment and prophylaxis of Pneumocystis carinii pneumonia, also causes pancreatitis by a direct toxic effect.
Oral eflornithine, the diamidine
prodrug DB 289, and the pre-clinical development of megazol seem promising.