dialysis disequilibrium syndrome

di·al·y·sis dis·e·qui·lib·ri·um syn·drome

nausea, vomiting, and hypertension, occasionally with convulsions, developing within several hours after starting hemodialysis for renal failure; apparently caused by too rapid removal of urea from the extracellular fluid compartment, with movement of water into cells, and cerebral edema.

dialysis disequilibrium syndrome

A neurologic condition linked to dialysis with signs of cerebral oedema.

Clinical finding
Headaches (often bilateral with throbbing), nausea, muscle cramps, hypertension, irritability, agitation, drowsiness, convulsions.
 
Mechanism
Uncertain; attributed to increased urea or organic compounds, either of which result in reverse osmosis.

di·al·y·sis dis·e·qui·lib·ri·um syn·drome

(dī-ali-sis dis-ēkwi-librē-ŭm)
Nausea, vomiting, and hypertension, occasionally with convulsions, developing within several hours after starting hemodialysis for renal failure.
References in periodicals archive ?
Dialysis related complications such as Intra dialytic leg cramps, Dialysis disequilibrium syndrome (DDS) and hemodynamic instabilities (Intra dialytic Hypo/hypertension) were significant concerning issues in our study, as is the case in most of the world literature6.
Dialysis disequilibrium syndrome (DDS), first described by Kennedy et al.
Arieff, "Dialysis disequilibrium syndrome: current concepts on pathogenesis and prevention," Kidney International, vol.
A rare but serious complication of dialysis is the so-called dialysis disequilibrium syndrome (DDS), defined as the occurrence of acute neurological symptoms attributed to cerebral edema and increased intracranial pressure (ICP) during or following dialysis [2].
Cotte, and P Goutorbe, "Dialysis disequilibrium syndrome in neurointensive care unit: the benefit of intracranial pressure monitoring," Critical Care, vol.
The high frequency of poor sleep quality in hemodialysis patients has been attributed to a lack of nocturnal endogenous melatonin surge [9], increased core body temperature from exposure to warm dialysate [10], and possibly cerebral edema in the context of dialysis disequilibrium syndrome [11].
When discussing ICP changes during HD, many existing papers further relate to the topic of dialysis disequilibrium syndrome (DDS).
It is preferred over hemodialysis in cases of acute kidney injury associated with bleeding tendency, hypotension and cardiovascular instability since it runs continuously with slow chemical changes and without risk of dialysis disequilibrium syndrome. It is the treatment of choice for neonates and infants due to technical reasons8-10.
Study of 100 patients is insufficient to cover rare complications like dialysis disequilibrium syndrome, cardiac arrest, myocardial infarction, stroke etc.
The symptoms are given different names throughout the literature, including dialysis intolerance, dialysis disequilibrium syndrome, vascular instability syndrome, and dialysis fatigue.
Dialysis disequilibrium syndrome (DDS) is a neurologic syndrome precipitated by osmolar shifts in patients with very high BUNs receiving dialysis treatment.