Hayman developed the best-known methods for diallelic
analysis, exclusively for homozygous parents (Hayman, 1954a and b).
In the case of multiple alleles for modes (2) and (3), these distributions were reduced to diallelic
Using (at that time) a sophisticated computer analysis of the reaction patterns of 60 sera from multiparous women against leucocytes from a panel of 100 donors, van Rood found some sera that apparently detected a diallelic
system of leucocyte antigens, which he called 4a and 4b (later to become HLA-Bw4 and -Bw6, respectively).
crossing is one of the tools that can be employed for the best genotypes (Lima and Cardoso, 2000).
Insertion and/or deletion (indels) polymorphisms are diallelic
markers with the potential for use in the study of genetic diversity and phylogenic relationships.
Polymorphism and ratio of peak areas in trisomy 21 samples STR marker Triallelic Diallelic
Monoallelic samples (n) samples (n) samples (n) D21S1435 25 38 7 D21S11 33 34 3 D21S1270 44 24 2 D21S226 5 46 19 D21S1411 36 31 3 IFNAR 28 40 2 STR marker Ratio of peak areas in diallelic
samples Range Mean SD D21S1435 2.65-1.14 1.81 0.32 D21S11 2.53-1.38 1.92 0.24 D21S1270 3.05-1.06 1.97 0.54 D21S226 3.35-1.46 2.05 0.35 D21S1411 2.49-1.52 2.08 0.24 IFNAR 2.65-1.40 1.99 0.28 FIGURE 1.
An NR3C1 diallelic
single nucleotide polymorphism, Bcl-1, has been reported to distinguish individuals with the highest GC sensitivity.(6) The aim of the present study was to investigate the association between the NR3C1 gen (Bcl-1-CG) polymorphism and the response to therapy among RA patients and healthy control subjects.
The particular model of fitness landscapes that we consider here begins with an idealized collection of all genotypes that are haploid and diallelic
at n loci.
The two remaining loci (AAT-1, LDH) are both diallelic
systems that resolve well in adults, but since LDH could not be consistently scored in spiderlings during preliminary testing, probably due to a low level of enzyme concentration in their homogenates, only AAT-1 (a cationic locus) was used in this study.
Of 269 diallelic
sites (SNPs), 173 (64%) were in the CC study samples and 59 (34%) were unique to the CC study samples (Table 2, online Technical Appendix).