diagnostic specificity

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Related to diagnostic specificity: diagnostic sensitivity

di·ag·nos·tic spec·i·fic·i·ty

the probability (P) that, given the absence of disease (D), a normal test result (T) excludes disease; that is, P(T/D).

diagnostic specificity

the conditional probability that a person not having a disease will be correctly identified by a clinical test, i.e., the number of true negative results divided by the total number of those without the disease (which is the sum of the numbers of true negative plus false positive results).

di·ag·nos·tic spe·ci·fi·ci·ty

(dī-ăg-nos'tik spes'i-fis'i-tē)
1. The probability (P) that, given the absence of disease (D), a normal test result (T) excludes disease; i.e., P(T/D).
2. Specificity (%) = number of patients without the disease who test negative × 100 ÷ total number tested without the disease.

diagnostic specificity

For a diagnostic or screening test, the proportion of people who are truly free of a specific disease and are so identified by the test.
See: sensitivity
See also: specificity
References in periodicals archive ?
This group reduced the diagnostic specificity of using the 99th-percentile value alone.
The [greater than or equal to] 99th percentile or percent [delta] of >10%, 20%, and 30% or the biological and analytical variability of hs-cTnT of 84% to look for improvement in early diagnostic sensitivity and assess diagnostic specificity.
Diagnostic specificity, sensitivity, and efficiency are markedly influenced by changes in the GC-MS confirmation cutoff.
Although measurement of plasma fractionated metanephrines has a diagnostic sensitivity of 96% to 100%, the diagnostic specificity is suboptimal at 85% to 89%; the diagnostic specificity falls to 77% in patients older than 60 years.
The high levels of diagnostic specificity of our PCPs, the degree of actual agreement with ratings by psychiatrists and a fair Kappa coefficient are remarkable when compared with other studies.
Do you mean to question diagnostic specificity of psychiatric disorders?
14) The presence of RF in so many other conditions decreases the diagnostic specificity of the RF test, resulting in the search for a more specific test for the diagnosis of RA.
Such an approach "undervalues the diagnostic specificity of the cutaneous changes of dermatomyositis" and underemphasizes the profound clinical impact of cutaneous inflammation on patients' quality of life, he said.
This new test for appendicitis will provide clinicians with a rapid, non-invasive assay that is easy to administer, has high diagnostic specificity and can potentially reduce unnecessary hospitalizations and surgeries.
In response to the anthrax emergency of 2001, we report the accelerated development and qualification of a quantitative ELISA for detection of anti-protective antigen (PA) specific immunoglobulin (Ig) G in human serum and the development of a competitive inhibition assay to enhance diagnostic specificity.
Predictive values include: (a) diagnostic sensitivity (percent of individuals with the disease who test positive by the assay), (b) diagnostic specificity (percent of individuals without the disease who test negative by the assay), (c) diagnostic efficiency (percent of all test results that are either true positives or true negatives), (d) positive predictive value (percent of all positive test results that are true positives), and (e) negative predictive value (percent of all negative test results that are true negatives).

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