diabetic polyneuropathy

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di·a·bet·ic pol·y·neu·rop·a·thy

a distal, symmetric, generally sensorimotor polyneuropathy that is a frequent complication of diabetes mellitus.

diabetic polyneuropathy

a disorder involving a number of nerves, a long-term complication of diabetes mellitus. Central nervous system, autonomic, and peripheral nerves may be affected. Neuropathic ulcers commonly develop on the feet.


(pol?e-noo-rop'a-the) [ poly- + neuropathy]
Any disease that affects multiple peripheral nerves.

acute inflammatory demyelinating polyneuropathy

Guillain-Barré syndrome.

acute inflammatory polyneuropathy

Guillain-Barré syndrome.

amyloid polyneuropathy

Polyneuropathy characterized by deposition of amyloid in nerves.

chronic inflammatory demyelinating polyneuropathy

Abbreviation: CIDP
A gradually progressing autoimmune muscle weakness in arms and legs caused by inflammation of the myelin sheath covering peripheral nerve axons. Demyelination slows or blocks conduction of impulses to muscles. Numbness and paresthesia may accompany or precede loss of motor function, which varies from mild to severe. Laboratory findings include elevated protein levels in the cerebrospinal fluid. The inflammatory damage involves not only phagocytes (neutrophils and macrophages), but also immune complexes and complement activation by myelin autoantigens. Immunosuppressive drugs are used to treat this illness. Plasma exchange therapy or infusions of immunoglobulins often are used first, to produce a remission. CIDP is considered to be a chronic counterpart to Guillain-Barré syndrome.

critical illness polyneuropathy

Abbreviation: CIP
A complication occurring in patients in intensive care in which failure to wean from mechanical ventilation is associated with distal limb weakness, loss of distal sensation from light touch or pinprick, and diminished reflexes; facial muscles and nerves are spared. Recovery typically occurs several weeks or months after resolution of the underlying disease. It is associated with the use of drugs, such as corticosteroids or paralytic agents, and neurological illnesses, such as Guillain-Barre syndrome.

diabetic polyneuropathy

Diabetic neuropathy.

familial amyloiditic polyneuropathy

An inherited form of amyloid polyneuropathy in which abnormal forms of transthyretin are deposited in nerves and brain tissue, making multiple nerves malfunction.

paraproteinemic polyneuropathy

Polyneuropathy due to excessive levels of immunoglobulin in the blood. The most commonly implicated immunoglobulins are IgM and IgG.

porphyric polyneuropathy

Polyneuropathy due to acute porphyria, characterized by pains and paresthesias in the extremities and by flaccid paralysis.

progressive hypertrophic polyneuropathy

Déjérine-Sottas disease.
References in periodicals archive ?
Earlier studies with a rat model of diabetic polyneuropathy, showed a reduction in intraepidermal nerve fiber density in skin biopsies, as well as a decrease in the loss of intraepidermal innervation upon therapeutic interventions (Bianchi et al.
Though the subjective pain sensation is comparable in Diabetic Polyneuropathy and Post-Herpetic Neuralgia (PHN), but the rate of improvement is slower in PHN than DPN with these medications.
Effects of 3-week oral treatment with the antioxidant thioctic acid (alpha-lipoic acid) in symptomatic diabetic polyneuropathy.
Previous studies demonstrated a benefit of SPK transplant for diabetic polyneuropathy.
Efficacy and safety of high-close a-lipoic acid in the treatment of diabetic polyneuropathy.
A 52-year-old woman with disabling peripheral neuropathy: Review of diabetic polyneuropathy.
Prevalence and characteristics of diabetic polyneuropathy in Passo Fundo, South of Brazil.
In the literature reviewed, most of case reports of ESFA are associated with reactive conditions like burn scar ulcer, bullous pemphigoid, erosive palmoplantar lichen planus and peristomal skin or associated with numerous conditions like nevus sebaceous, hidrotic ectodermal dysplasia, and diabetic polyneuropathy.