diabetic polyneuropathy

Also found in: Dictionary.

di·a·bet·ic pol·y·neu·rop·a·thy

a distal, symmetric, generally sensorimotor polyneuropathy that is a frequent complication of diabetes mellitus.

diabetic polyneuropathy

a disorder involving a number of nerves, a long-term complication of diabetes mellitus. Central nervous system, autonomic, and peripheral nerves may be affected. Neuropathic ulcers commonly develop on the feet.


(pol?e-noo-rop'a-the) [ poly- + neuropathy]
Any disease that affects multiple peripheral nerves.

acute inflammatory demyelinating polyneuropathy

Guillain-Barré syndrome.

acute inflammatory polyneuropathy

Guillain-Barré syndrome.

amyloid polyneuropathy

Polyneuropathy characterized by deposition of amyloid in nerves.

chronic inflammatory demyelinating polyneuropathy

Abbreviation: CIDP
A gradually progressing autoimmune muscle weakness in arms and legs caused by inflammation of the myelin sheath covering peripheral nerve axons. Demyelination slows or blocks conduction of impulses to muscles. Numbness and paresthesia may accompany or precede loss of motor function, which varies from mild to severe. Laboratory findings include elevated protein levels in the cerebrospinal fluid. The inflammatory damage involves not only phagocytes (neutrophils and macrophages), but also immune complexes and complement activation by myelin autoantigens. Immunosuppressive drugs are used to treat this illness. Plasma exchange therapy or infusions of immunoglobulins often are used first, to produce a remission. CIDP is considered to be a chronic counterpart to Guillain-Barré syndrome.

critical illness polyneuropathy

Abbreviation: CIP
A complication occurring in patients in intensive care in which failure to wean from mechanical ventilation is associated with distal limb weakness, loss of distal sensation from light touch or pinprick, and diminished reflexes; facial muscles and nerves are spared. Recovery typically occurs several weeks or months after resolution of the underlying disease. It is associated with the use of drugs, such as corticosteroids or paralytic agents, and neurological illnesses, such as Guillain-Barre syndrome.

diabetic polyneuropathy

Diabetic neuropathy.

familial amyloiditic polyneuropathy

An inherited form of amyloid polyneuropathy in which abnormal forms of transthyretin are deposited in nerves and brain tissue, making multiple nerves malfunction.

paraproteinemic polyneuropathy

Polyneuropathy due to excessive levels of immunoglobulin in the blood. The most commonly implicated immunoglobulins are IgM and IgG.

porphyric polyneuropathy

Polyneuropathy due to acute porphyria, characterized by pains and paresthesias in the extremities and by flaccid paralysis.

progressive hypertrophic polyneuropathy

Déjérine-Sottas disease.
References in periodicals archive ?
Clinical diagnosis of diabetic polyneuropathy with the diabetic neuropathy symptom and siabetic neuropathy examination scores.
Constipation and fecal impaction are common symptoms in patients with neurologic disorders (traumatic spinal cord injuries, spina bifida, multiple sclerosis, diabetic polyneuropathy, Parkinson's disease, stroke, and cerebral palsy).
But it's also significant because drugs that are useful for painful diabetic polyneuropathy will most likely be adopted [in the treatment of] neuropathic pains more generally.
The sensory symptoms of diabetic polyneuropathy are improved with alpha-lipoic acid: the SYDNEY trial.
A randomized, placebo-controlled, double-blind, two-center pilot study evaluated the efficacy of benfotiamine in the treatment of diabetic polyneuropathy.
The influence of Neurobion on temperature sensibility in patients with diabetic polyneuropathy, Int.
The role of alpha-lipoic acid in diabetic polyneuropathy treatment.
Results: Fifty-six patients with diabetic polyneuropathy (71%) or PHN neuralgia (29%) were enrolled and randomized.
In a reversal of two decades of medical reports, a Mayo Clinic study finds the frequency of nerve damage called diabetic polyneuropathy is similar in prediabetic patients and healthy people.
7 years) and diabetic polyneuropathy were randomly assigned to receive, in double-blind fashion, 400 mg of coenzyme Q10 (CoQ10) once a day or placebo for 12 weeks.