diabetic cataract


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di·a·bet·ic cat·a·ract

cataract occurring in Type 1 diabetes.
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Inhibitory Effect of Crocin(s) on Lens [alpha]-Crystallin Glycation and Aggregation, Results in the Decrease of the Risk of Diabetic Cataract. Molecules.
Our group was interested in finding clear recommendations for screening for early diabetic cataract in the pediatric population but was not able to find guidelines.
For diabetic patients, chronic inflammation and oxidative stress can progress to diabetic cataracts [103].
Therefore, the data indicated that melatonin delayed the onset and maturation of diabetic cataract.
To date, a number of AR inhibitors (ARI) have been developed for the treatment of diabetic cataract. For example, a proprietary formulation of an ARI improved functional vision in diabetic dogs with early lens opacities [7].
Ginger was effective against the development of diabetic cataract in rats mainly through its antiglycating potential and ginger may be explored for the prevention or delay of diabetic complication.
Early symptoms of adult-onset diabetic cataract are persistent refractive changes, glare, and monocular diplopia or polyopia.
Our study confirmed that the risk of developing preproliferative retinopathy, diabetic macular edema and diabetic cataract increases with increasing duration of diabetes.
At present, the prevalence of diabetic eye complications such as diabetic cataract and diabetic retinopathy, the leading causes of an acquired blindness, is increasing due to the survival of diabetic patients.
Lens osmotic expansion, a crucial and reversible process, greatly triggers the rapid onset and accelerates the maturation of true cataract [3]; thus, this is the critical stage for the prevention of diabetic cataract. Cell swelling is the main feature of lens osmotic expansion; several proteins such as AR, P-gp, and Clcn3 are proposed to participate in this pathological mechanism.
Diabetic cataract differs from the age-related cataract; the robust factor is not the oxidative stress but the osmotic expansion of lens.
Processes underlying the most common forms of cataracts, senile cataract and diabetic cataract, require further research as the causes can be multifactorial.