dextropropoxyphene


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propoxyphene

 [pro-pok´sĭ-fēn]
an opioid analgesic administered orally as the hydrochloride and napsylate salts; called also dextropropoxyphene.

dextropropoxyphene

A painkilling drug similar to METHADONE. It is also dispensed in combination with paracetamol, as Distalgesic. Overdosage is one of the commonest causes of death by poisoning, as absorption is rapid and breathing is quickly paralysed. It is not much more effective than CODEINE and some poisoning experts think it should be withdrawn. A brand name is Doloxene.
References in periodicals archive ?
Danas Pharmaceutical, in its request, maintained the 5,000kg dextropropoxyphene quota was intended for flood victims.
Among the active-controlled trials, participants taking tramadol were more likely to report a major AE compared with those receiving either diclofenac or dextropropoxyphene (NNH=5), but less likely compared with patients taking pentazocine.
Results of a new study show that, even at doses normally taken to manage pain, dextropropoxyphene can significantly increase the risk of serious abnormal heart rhythms.
Results: Significant (P<0.001) increase in comet tail length and % MnPCE was observed in both acute and subacute studies of cyclophosphamide group, whereas codeine, dextromethorphan and dextropropoxyphene treated groups did not show any significant changes.
The common opioids used were; dextropropoxyphene (25.4 %), codeine cough syrup (9 %) and heroine (6 %).
The Dubai Court of First Instance sentenced the 47-year-old man to life after he was found guilty of possessing 191 Dextropropoxyphene (a tranquiliser) with the intent to sell.
Types of drugs injected Pure dextropropoxyphene /dicylomine 31 13 41.9 (proxyvon) users Both proxyvon and heroin users 85 66 77.6 Only heroin user 27 23 85.2 11.
Coroner Philip Walters said the cause of death was alcohol and dextropropoxyphene overdose.
It contains a combination of two pain-killing ingredients, paracetamol and dextropropoxyphene hydrochloride.
In 7 of the falls precipitated by drugs, the judgment was that there had been an overdose (various combinations of benzodiazepines, dextropropoxyphene, propiomazine, levomepromazine [not available in the US], and carbamazepine) in 1 resident who had problems with addiction to drugs and alcohol.
The following drugs were checked: granisetron, ondansetron, tropisetron, dolasetron, alizapride, zolpidem, tianeptine, methylprednisolone, fluoxetine, dextropropoxyphene, acetaminophen, enoxaparin, nifedipine, bromazepam, lorazepam, chlorazepate, levothyroxine, zopiclone, tinzaparin, cetirizine, simvastatin, famotidine, glibenclamide, and omeprazole.
It's a mixture of paracetomol, which is a non- narcotic analgesic drug, and the mildly-narcotic analgesic, dextropropoxyphene.