dextran
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dextran
[dek´stran]a water-soluble polysaccharide of glucose produced by the action of Leuconostoc mesenteroides on sucrose; used as an artificial plasma extender.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.
dex·tran
(deks'tran),1. Any of several water-soluble high molecular weight glucose polymers (ranging between MW 1,000 and 40,000,000); produced by the action of members of the family Lactobacillaceae and certain other microorganisms on sucrose; used in isotonic sodium chloride solution for the treatment of shock, and in distilled water for the relief of the edema of nephrosis; lower molecular weight dextran (for example, MW 40,000 designated as dextran 40) improves blood flow in areas of stasis by reducing cellular aggregation.
See also: dextransucrase.
See also: dextransucrase.
2. α-1,6-glucan with branch points (1,2; 1,3; 1,4) that are spaced in a manner characteristic of the individual species; used as plasma substitutes or expanders.
See also: dextransucrase.
See also: dextransucrase.
Farlex Partner Medical Dictionary © Farlex 2012
dextran
(dĕk′străn′, -strən)n.
Any of a group of branched polysaccharides with various molecular weights that are used to prevent thrombosis, as plasma volume expanders, and as food additives.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.
dextran
Transfusion medicine Dextran-40, dextran-70, dextran-1 A colloid-type volume expander consisting of a large glycogen-like molecules which may occasionally be used in surgical blood management by hemodilution; these substances have the desired properties of being viscid, and gelatinous, resulting in oncotic pressure to retain fluids in vessels; they are widely used as replacement fluids and volume expanders Pros ↓ Allogeneic transfusions, ↓ postoperative bleeding, ↓ blood viscosity Cons Interferes with platelet and RBC function, crossmatching; may cause anaphylaxis and peripheral edema. See Colloid solutions, Crystalloids, Hemodilution, Surgical blood management.McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.
dex·tran
(deks'tran)Any of several water-soluble high molecular weight glucose polymers; used in isotonic sodium chloride solution for the treatment of shock, and in distilled water for the relief of the edema of nephrosis; lower molecular weight dextran.
See also: dextransucrase
See also: dextransucrase
Medical Dictionary for the Health Professions and Nursing © Farlex 2012
dex·tran
(deks'tran)Any of several water-soluble high molecular weight glucose polymers; used in isotonic sodium chloride solution to treat shock and to relieve edema of nephrosis.
Medical Dictionary for the Dental Professions © Farlex 2012