dextran


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Related to dextran: dextrin, dextran 70, dextran sulfate

dextran

 [dek´stran]
a water-soluble polysaccharide of glucose produced by the action of Leuconostoc mesenteroides on sucrose; used as an artificial plasma extender.

dex·tran

(deks'tran),
1. Any of several water-soluble high molecular weight glucose polymers (ranging between MW 1,000 and 40,000,000); produced by the action of members of the family Lactobacillaceae and certain other microorganisms on sucrose; used in isotonic sodium chloride solution for the treatment of shock, and in distilled water for the relief of the edema of nephrosis; lower molecular weight dextran (for example, MW 40,000 designated as dextran 40) improves blood flow in areas of stasis by reducing cellular aggregation.
See also: dextransucrase.
2. α-1,6-glucan with branch points (1,2; 1,3; 1,4) that are spaced in a manner characteristic of the individual species; used as plasma substitutes or expanders.
See also: dextransucrase.

dextran

/dex·tran/ (dek´stran) a high-molecular-weight polymer of d-glucose, produced by enzymes on the cell surface of certain lactic acid bacteria. Dextrans formed from sucrose by bacteria in the mouth adhere to the tooth surfaces and produce dental plaque. Uniform molecular weight dextrans from Leuconostoc mesenteroides preparations are used as plasma volume expanders, with specific preparations named for their average molecular weight.

dextran

(dĕk′străn′, -strən)
n.
Any of a group of branched polysaccharides with various molecular weights that are used to prevent thrombosis, as plasma volume expanders, and as food additives.

dextran

Transfusion medicine Dextran-40, dextran-70, dextran-1 A colloid-type volume expander consisting of a large glycogen-like molecules which may occasionally be used in surgical blood management by hemodilution; these substances have the desired properties of being viscid, and gelatinous, resulting in oncotic pressure to retain fluids in vessels; they are widely used as replacement fluids and volume expanders Pros ↓ Allogeneic transfusions, ↓ postoperative bleeding, ↓ blood viscosity Cons Interferes with platelet and RBC function, crossmatching; may cause anaphylaxis and peripheral edema. See Colloid solutions, Crystalloids, Hemodilution, Surgical blood management.

dex·tran

(deks'tran)
Any of several water-soluble high molecular weight glucose polymers; used in isotonic sodium chloride solution for the treatment of shock, and in distilled water for the relief of the edema of nephrosis; lower molecular weight dextran.
See also: dextransucrase

dex·tran

(deks'tran)
Any of several water-soluble high molecular weight glucose polymers; used in isotonic sodium chloride solution to treat shock and to relieve edema of nephrosis.

dextran (dek´stran),

n (C6H10O5) a water-soluble polymer of glucose of high molecular weight. A purified form, having an average molecular weight of 75,000, is used in a 6% concentration in isotonic sodium chloride solution to expand plasma volume and maintain blood pressure in emergency treatment of hemorrhagic and traumatic shock.

dextran

a water-soluble polysaccharide of glucose (dextrose) produced by the action of Leuconostoc mesenteroides on sucrose; used as a plasma volume extender. Several preparations of dextran are used as anticoagulants.

dextran 40
used as an adjuvant in blood transfusion, an anticoagulant.
dextran sulfate
used as an anticoagulant and recently investigated for its antiviral activity.
References in periodicals archive ?
Polydex reported income from operations at the Dextran plant of $211,260, an increase over the 3rd quarter of fiscal 2001 of $93,163, however Vet Labs income from operations during the same period amounted to $3,045, a decrease of $354,265.
HPMC and dextran generally improved dough and bread quality.
Dextran coated nanoparticles are widely used in imaging by magnetic resonance (MRI), optical and positron emission tomography (PET) as contrast agents.
The efficacy of iron dextran has long been established from many clinical trials dating back to the 1980s.
elatior protoplasts is enzyme solution E composed of 3% Cellulase "Onozuca" R-10, 2% Meicelase, 1% Driselase, 1% Dextran and 5 mM MES combined with 0.
The specific gravity of the dextran solutions and the observed gel flotation patterns following centrifugation are shown in the Table.
Our laboratory has measured HDL-C and LDL-C directly in frozen plasma with the kits from one of the manufacturers (Kyowa Medex) and compared the results with those obtained with the dextran sulfate [Mg.
A 500 kDa dextran, with an estimated diameter of about 14.
On the other hand, it did not inhibit the edema and the increase of vascular permeability induced by dextran in the rat paw.
A prominent increase in alkaline protease production was obtained when the fermentation was carried out in ATPS containing PEG and dextran T500 but the very high viscosity and cost of dextran limits its use [5].
Another Jehovah's Witness said Witnesses requested that hospitals treat them with protein hormone EPO, folic acid, vitamin B12 and iron dextran as an alternative to receiving blood, with some success.
The first reagent contains a-cyclodextrin and dextran sulfate to stabilize LDL-C, VLDL, and chylomicrons.