dexchlorpheniramine


Also found in: Wikipedia.

dexchlorpheniramine

 [deks″klor-fen-ir´ah-mēn]
the dextrorotatory isomer of chlorpheniramine, having similar actions and uses as an antihistamine, but having approximately twice the activity by weight; used in the form of the maleate salt.
References in periodicals archive ?
Rohman, "Validation of an ion-pair high performance liquid chromatography for the determination of pseudoephedrine HCl, guaifenesin and dexchlorpheniramine maleat in cough and cold medicines," International Journal of Pharmaceutical and Clinical Research, vol.
Characteristics Pediatric medicine Active ingredient Concentration G1 (Alivium[R]) Ibuprofen 30 mg/mL G2 (Novalgina[R]) Dipyrone 50 mg/mL G3 (Betamox[R]) Amoxicillin and mg/5 mL + 62.5 mg/5 mL Clavulanic Acid 250 G4 (Clavulin[R]) Amoxicillin and mg/5 mL + 62.5 mg/5 mL Clavulanic Acid 250 G5 (Claritin[R]) Loratadine 1 mg/mL G6 (Polaramine[R]) Dexchlorpheniramine 2 mg/5 mL maleate G7 (Milli-Q water) -- -- Pediatric medicine Trademark pH at cold pH at room temperature temperature G1 (Alivium[R]) Mantecorp 4.37 3.70 G2 (Novalgina[R]) Sanofi-aventis 7.25 6.98 G3 (Betamox[R]) Atral 5.83 4.64 G4 (Clavulin[R]) SmithKline Beecham 5.48 5.50 G5 (Claritin[R]) Schering-Plough 3.85 2.10 G6 (Polaramine[R]) Mantecorp 6.72 6.27 G7 (Milli-Q water) -- 7.01 6.99 Table 2.
Sex hormones and insulins Antiparasitic products, 4.5 5.0 3.8 insecticides and repellents Sensory organs 0.9 0.0 0.0 Antineoplastic and 0.0 0.0 0.0 immunomodulating agents Mean (%) (SD) 32.2 35.1 27.6 (26.3) (27.5) (18.6) ATC system main groups Most prescribed drug Cardiovascular system Captopril/Enalapril Nervous system Metamizole sodium Blood and blood forming Acetylsalicylic acid ** organs Alimentary tract and Omeprazole metabolism * Musculo-skeletal system Diclofenac Antiinfectives for systemic use Amoxicillin Respiratory system Dexchlorpheniramine Genito urinary system and Miconazole sex hormones Dermatologicals Neomicyin, combination Systemic hormonal Levothyroxine sodium preparations, excl.
A meta-analysis of 11 RCTs (1317 patients, average age 32) showed no significant difference in relief of eye symptoms between oral antihistamines (dexchlorpheniramine, terfenadine, and loratadine) and intranasal steroids (budesonide, beclomethasone, fluticasone, and triamcinolone) in patients with seasonal allergies, as measured by various symptom scores?
(d) Diphenhydramine, doxylamine, dexchlorpheniramine, chlorpheniramine, promethazine, desloratadine, cyproheptadine, loratadine, fexofenadine, hydroxyzine, pheniramine, dimetindene.
(14) A total of 21 patients received loratadine syrup at 0.11 to 0.24 mg/kg ideal body weight once daily, and 19 children received first-generation dexchlorpheniramine syrup at 0.10 to 0.23 mg/kg every 8 hours.
Investigation of the reasons for failing to identify other target drugs gave the following results: drugs present but below the detection limit (n = 2), erythromycin and acetaminophen; drugs not yet established in the library entries at the time of analysis (n = 5), phenolphthalein, metoclopramide (2 occasions), cannabinoids, and dexchlorpheniramine.
The current recommendation is to discontinue the infusion and not retreat the patient; however, this recommendation is being reviewed and pre-treatment with hydrocortisone and dexchlorpheniramine appears to prevent these reactions.