(39.) Kilicarslan H, Ayan S, Vuruskan H, Gokce G, Gultekin EY Treatment of detrusor sphincter dyssynergia
with baclofen and doxazosin.
Different patterns of NB can that can be obtained on UDX testing including detrusor hyperreflexia/ overactivity (DO) which is defined as the urodynamic finding characterized by involuntary detrusor contraction, detrusor hyporeflexia/ areflexia/ acontractility (DA) which is defined as the urodynamic finding characterized by no or weak detrusor contraction, and detrusor sphincter dyssynergia
(DSD) defined as the urodynamic finding characterized by simultaneous contractions of both detrusor and urethral sphincter9-12.
The findings suggest that neurogenic bladder due to neuro-Behcet disease is characterized uro-dynamically by overactive detrusor in storage phase and detrusor sphincter dyssynergia
in voiding phase 12.
In patients with neurogenic disorders, EMG is used to diagnosing detrusor sphincter dyssynergia
Placebo-controlled, randomized, double-blind study of the effects of botulinum A toxin on detrusor sphincter dyssynergia
in multiple sclerosis patients.
of Percentage Cases Overactive bladder 11 18.64 Mixed (Stress urinary continence + 15 25.42 overactive bladder) Detrusor underactivity 19 Detrusor under activity + poor compliance 3 37.28 Normal 3 5.08 Genuine stress incontinence 2 3.38 Bladder outlet obstruction 3 5.08 DSD (Detrusor sphincter dyssynergia
) 2 3.38
After the period of spinal shock, complete suprasacral injuries result in detrusor hyperreflexia and detrusor sphincter dyssynergia
(DSD) (1,2) and complete sacral injuries result in detrusor areflexia (3).
* features of functional bladder outlet obstruction on electromyography, such as detrusor sphincter dyssynergia
Problems reported in some patients included detrusor sphincter dyssynergia
(high urethral resistance), poor voiding responses, leg contractions, and pain.
* Suprasacral spinal cord lesion (hyperreflexic bladder)--these patient present with a spastic bladder and internal sphincter and they often have DSD detrusor sphincter dyssynergia
) where there is a lack of co-ordination between the detrusor muscle and internal sphincter.
Joy and Johnston (2001) suggest that 90% of people with MS experience bladder dysfunction at some point; detrusor hyperreflexia, detrusor sphincter dyssynergia
, and detrusor areflexia are the three most common types.
Botox has also been studied in detrusor sphincter dyssynergia
(DSD), which causes urinary urgency, frequency, incontinence, difficulties emptying the bladder, and urinary infections in people with MS.