detrusor instability

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Related to detrusor instability: neurogenic bladder


lack of constancy; excessive likelihood of change.
detrusor instability the occurrence during bladder filling of contractions that compromise capacity or produce urinary leakage.

de·tru·sor in·sta·bil·i·ty

uninhibitable bladder contractions that typically occur at bladder volumes below capacity.

detrusor instability

A physiological mechanism in which contractions of the muscles of the urinary bladder during the filling phase of a urodynamic study or during coughing, sneezing, or other activities result in an increase of intra-abdominal pressures. Such a pressure increase may lead to urinary urges or to urinary incontinence, esp. in women. Some experts believe that detrusor instability is the most common cause of urinary incontinence in older adults. Underlying causes include urethral obstruction, cystitis, bladder carcinoma, stroke, Parkinson's disease, and multiple sclerosis. Synonym: detrusor hyperactivity with impaired contractility; detrusor overactivity;
See also: instability

detrusor instability

Involuntary contractions of the bladder muscle causing an undesired escape of urine. This is one of the most important causes of incontinence, being, in women, second only to incompetence of the urethral sphincter. The condition is often associated with excessive thickness of the muscular bladder wall.
References in periodicals archive ?
Oxybutynin hydrochloride (3 mg) in the treatment of women with idiopathic detrusor instability.
Q I AM a 21-year-old man and I have been told I have a bladder problem called congenital detrusor instability.
Soomro N, Khadra M, Robson W, et al: A crossover randomized trial of transcutaneous electrical nerve stimulation and oxybutynin in patients with detrusor instability.
Detrusor instability and bladder outlet obstruction.
Other contraindications include an atonic detrusor with an elevated postvoid residual, uncontrolled and severe detrusor instability, vesicoureteral reflux, vesico- or urethrovaginal fistula, or a history of pelvic radiation.