antigenic determinant

(redirected from determinant group)
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determinant

 [de-ter´mĭ-nant]
a factor that establishes the nature of an entity or event.
antigenic determinant a site on the surface of an antigen molecule to which a single antibody molecule binds; generally an antigen has several or many different antigenic determinants and reacts with many different antibodies. Called also epitope.
 Antigens contain antigenic determinants (epitopes) and antibodies contain antibody combining sites (paratopes). From Copstead and Banasik, 2000.
hidden determinant an antigenic determinant located in an unexposed region of a molecule so that it is prevented from interacting with receptors on lymphocytes, or with antibody molecules, and is unable to induce an immune response; it may appear following stereochemical alterations of molecular structure.
immunogenic determinant the part of an immunogenic molecule that interacts with a helper T cell in triggering antibody production as opposed to the antigenic determinant or hapten, which interacts with B cells.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

an·ti·gen·ic de·ter·mi·nant

the particular chemical group of a molecule that determines immunologic specificity.
Synonym(s): determinant group
Farlex Partner Medical Dictionary © Farlex 2012

an·ti·gen·ic de·ter·mi·nant

(an'ti-jen'ik dĕ-tĕr'mi-nănt)
The particular chemical group of a molecule that determines immunologic specificity.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012

antigenic determinant

A cluster of EPITOPES.
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005

antigenic determinant

see EPITOPE.
Collins Dictionary of Biology, 3rd ed. © W. G. Hale, V. A. Saunders, J. P. Margham 2005