desthiobiotin

des·thi·o·bi·o·tin

(des'thī-ō-bī'ō-tin),
A compound derived from biotin by the removal of the sulfur atom; a precursor of biotin in bacteria and molds; it can substitute for biotin in some microorganisms, but is without effect on or is inhibitory to the growth of others.
Farlex Partner Medical Dictionary © Farlex 2012
References in periodicals archive ?
The Strep-tagged or SBP-fused proteins can be dissociated from the ligand covalently attached to agarose resin by elution buffer with biotin or desthiobiotin [27, 28].
After extensive washing with equilibration buffer containing 1 mmol/L phenylmethylsulfonyl fluoride at a flow rate of 0.9 mL/ [cm.sup.2] per minute, the protein was eluted with equilibration buffer containing 1 mmol/L phenylmethylsulfonyl fluoride and 2.5 mmol/L desthiobiotin (Sigma) at a flow rate of 0.4 mL/[cm.sup.2] per minute.
The protein could be purified in a single step by affinity binding to a StrepTactin column; on washing with desthiobiotin, the protein eluted as a single band with an estimated molecular mass of 87 kDa (Fig.