desquamative interstitial pneumonitis

desquamative interstitial pneumonia

A generally mild, nonspecific interstitial pulmonary reaction that is a double misnomer—as it is neither desquamative nor interstitial—which is characterised by diffuse deposition of haemosiderotic macrophages. DIP is often idiopathic but may be associated with inhalation of inorganic dusts.

Demographics
Most patients are smokers and adults; DIP rarely occurs in children, in whom it has a worse prognosis.

Prognosis
Better prognosis and response to steroids than UIP (in adults).

Imaging
Bilateral ground-glass opacification.
 
DiffDx
Smoking (RBILD), amiodarone therapy, eosinophilic pneumonia, pulmonary alveolar proteinosis.

Management
Corticosteroids.

desquamative interstitial pneumonitis

A nonspecific interstitial pulmonary reaction of adults; DIP is often idiopathic but may be associated with inhalation of inorganic particles  Radiology Bilateral ground-glass opacifications Treatment Corticosteroids. See Diffuse alveolar damage.
References in periodicals archive ?
The histological patterns of CADM-ILD vary and include desquamative interstitial pneumonitis, usual interstitial pneumonia (UIP), non-specific interstitial pneumonia (NSIP), and diffuse alveolar damage (DAD) (5).
Fibrosing alveolitis and desquamative interstitial pneumonitis.
Familial interstitial lung disease in children: response to chloroquine treatment in one sibling with desquamative interstitial pneumonitis.
It should be noted that some cases of congenital PAP may have pathologic findings of desquamative interstitial pneumonitis on transbronchial biopsy, with typical PAP histologic findings only in subpleural areas.