Also found in: Dictionary, Encyclopedia, Wikipedia.


a mineralocorticoid with no glucocorticoid activity, secreted in small amounts by the human adrenal cortex. It is used with a glucocorticoid for replacement therapy in adrenocortical insufficiency and addison's disease and for treatment of salt-losing adrenogenital syndrome.


A steroid derived from the adrenal cortex with strong mineralocorticoid activity.


An active steroid hormone produced by the adrenal cortex. It plays an important role in the regulation of water and salt metabolism.

desoxycorticosterone acetate

An acetate ester of desoxycorticosterone and the form in which the hormone is usually administered in its therapeutic use. It may be injected intramuscularly or used buccally.
References in periodicals archive ?
Clinical investigation on the use of CoQ for treatment of hypertension began when Igarashi et al (19) reported that CoQ reduced elevated blood pressure in unilaterally nephrectomized rats treated with desoxycorticosterone and saline.
Igarashi T, Tanabe Y, Nakajiima Y, et al: Effect of coenzyme Q10 on experimental hypertension in the desoxycorticosterone acetate-saline loaded rats.