23) More specifically, higher doses of estrogen combined with the progesterones gestodene, desogestrel
, and levonorgestrel, are associated with a higher risk of VTE.
on clinical and biochemical parameters in patients with polycystic ovary syndrome.
, gestodene, cyproterone acetate and drospirinone) are clearly second choice behind the second- and first-generation progestins.
After accounting for smoking, obesity, a wide range of other health conditions, alcohol consumption, polycystic ovary syndrome and recent infections, surgeries, leg/hip fractures, and hospital admission, the researchers calculated an increased odds ratio for each hormone: desogestrel
Women using newer pills, containing drospirenone, desogestrel
, gestodene, and cyproterone, had around a four times increased risk of VTE.
Phase III clinical trial with a new oral contraceptive containing 150 microgram desogestrel
and 20 microgram ethinylestradiol.
Comparative study of the effectsof a progestogen-only pill containing desogestrel
and anintrauterine contraceptive device in lactating women.
Combined OCPs administered to the patients included the following: desogestrel
Talk to your health care professional about a pill formulation with progestins that do not have an androgen effect and which are known to elevate SHBG, such as norgestimate, drospirenone or desogestrel
As well as this targeted review, the European Medicines Agency (EMA) is currently carrying out an overall review of combined contraceptives containing the following progestatives: chlormadinone, desogestrel
, dienogest, drospirenone, etonogestrel, gestodene, nomegestrol, norelgestromine and norgestimate.
a review of combined contraceptives containing chlormadinone, desogestrel
, dienogest, drospirenone, etonogestrel, gestodene, nomegestrol, norelgestromin and norgestimate
The authors, led by Dr Ojvind Lidegaard from the University of Copenhagen, say that women on pills containing one of the newer types of progestogen hormone (drospirenone, desogestrel
or gestodene) have double the risk of VTE than women on pills containing an older progestogen (levonorgestrel).