desmosome

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des·mo·some

(dez'mō-sōm),
A site of adhesion between two epithelial cells consisting, in each cell, of a dense attachment plaque with associated intermediate filaments and transmembrane proteins known as cadherins.
[desmo- + G. sōma, body]
Farlex Partner Medical Dictionary © Farlex 2012

des·mo·some

(des'mō-sōm)
A site of adhesion between two epithelial cells, consisting of a dense attachment plaque separated from a similar structure in the other cell by a thin layer of extracellular material.
Synonym(s): macula adherens.
[desmo- + G. sōma, body]
Medical Dictionary for the Health Professions and Nursing © Farlex 2012

desmosome

a thickened zone in the cell membrane of adjacent eukaryote cells.
Collins Dictionary of Biology, 3rd ed. © W. G. Hale, V. A. Saunders, J. P. Margham 2005

desmosome

A site of adhesion between two adjacent cells, such as in the corneal epithelium. It consists of a small, dense body in which the two halves are separated by an intercellular gap filled with extracellular substance. The basal cells are attached at irregular intervals to the underlying basement membrane (adjacent to Bowman's layer) by hemidesmosomes (one half of a desmosome). Thus, scraping off the epithelium usually leaves fragments of the basal cells attached to the basement membrane.
Millodot: Dictionary of Optometry and Visual Science, 7th edition. © 2009 Butterworth-Heinemann
References in periodicals archive ?
However, autoantibodies against various targets can be found, including desmosomal proteins Dsg1 and Dsg3, plakin family proteins (periplakin, envoplakin, plectin, desmoplakin, and BP180), and the protease inhibitor alpha-2-macroglobulin-like antigen 1 (A2ML1) (3, 20, 23).
We highlight the atypical presentation which may be associated with the difference of autoantibodies to desmosomal proteins in pemphigus patients.
Relatively recent studies have revealed that approximately 50-60% of patients with ARVC have a mutated gene encoding a desmosomal protein [28-30].
(13) Breakthroughs in this setting informed the field that dysfunctional desmosomes may be the root of the disease and led to the discovery of many desmosomal genes implicated in AC (Table 2).
Spinous layer cells are distinguished by the presence of desmosomal connections, whereas granular layer cells are characterized by the presence of granules that contain the products of keratinocyte differentiation.
(16.) Yamaoka Y, Sawa Y, Ebata N, Yoshida S, Kawasaki T Desmosomal Proteins In Cultured And Intact Human Periodontal Ligament Fibroblasts Tissue Cell 1999; 31 (6):605-609
(26) KFAP's also known as intermediate filament associated proteins are composed of filaggrin, tricohyalin, desmosomal proteins and proteins of cornified cell envelope (loricrin, involucrin and small proline rich proteins).
"Perp deficiency caused defects in desmosomal protein expression in breast epithelial cells," Dr Attardi said.
Additionally, expression of several gene transcripts such as heat shock protein 70 (Hsp70), interferon tau (IF-tau), DNA methyl-transferase 3a (Dnmt3a), desmosomal glycoprotein desmocollin III (DcIII) and insulin-like growth factor II receptor (Igf-2r) were altered in accordance to different culture conditions (6).
Desmosomal proteins: new markers for identification and classification of tumors.
The plakoglobin, desmoplakin and desmocollin-2 are family members of desmosomal proteins that function as cell-cell adhesion junction, and are expressed in skin, heart and hair.5