SOX10 is highly expressed in desmoplastic
melanomas (DMs) and spindle cell melanomas (SCMs).
In addition to specimens with abundant mucin or an infiltrative or subcapsular lymph node metastasis (see Figure 1), polymerase chain reaction failure (B) or reduced tumor cell percentages (A, C through E) may result from resection specimens with prior chemotherapy/radiation therapy (A), abundant necrosis (B), a prominent desmoplastic
reaction (C), lymphocytic infiltration (D), or tumors with superficial ulceration and prominent neutrophil infiltration (E) (hematoxylin-eosin, original magnifications X40 [A through D] and X64 [E]).
The differential diagnosis of atypical spindle cell neoplasms on sun-damaged skin includes atypical fibroxanthoma (AFX), spindle cell or desmoplastic
melanoma (see melanocytic neoplasms below), spindle cell SCC, and leiomyosarcoma.
melanoma is frequently a consequence of DNA damage to cells exposed to ultraviolet light.
Of the 16 cases of soft-tissue desmoplastic
fibroblastoma, 15 were obtained from surgical procedures in the Department of Hand Surgery and one case of bone was derived from a surgical procedure in the Department of Orthopedic Oncology.
trichoepithelioma: a clinicopathological study of three cases and a review of the literature.
The histopathological reports of ameloblastoma were categorized as follicular, plexiform, acanthomatous, basal cell, desmoplastic
and granular cell types.
Some of the lymphoblastic lymphomas and a case of desmoplastic
small round cell tumour also showed FLI-1 positivity.
Waldron and El-Mofty discovered a unique variant of the ameloblastoma in 1987, displaying a combined histology of desmoplastic
and conventional ameloblastomas as a hybrid variant.
stroma was partly hyalinized and focally filled with lymphocytes and giant cells with washed needle crystals of cholesterol (Figure 3).
In the article titled "Primary Desmoplastic
Melanoma of the Penis" , the photomicrograph of S-100 immunohistochemical stain did not appear within the blackbox outline in Figure 2 in the PDF version.
ameloblastoma, including the so-called hybrid lesions.