desmoid


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desmoid

 [dez´moid]
1. an unencapsulated, locally invasive, and rarely metastasizing fibromatous tumor arising in the muscle sheath, usually of the abdominal wall, which closely resembles fibrosarcoma. Called also desmoid tumor.
2. fibroid (def. 1).

des·moid

(dez'moyd),
1. Fibrous or ligamentous.
2. A nodule or relatively large mass of unusually firm scarlike connective tissue resulting from active proliferation of fibroblasts, occurring most frequently in the abdominal muscles of women who have borne children; the fibroblasts infiltrate surrounding muscle and fascia. Synonym(s): abdominal fibromatosis, desmoid tumor
[desmo- + G. eidos, appearance, form]

desmoid

Aggressive fibromatosis, desmoid tumor, musculoaponeurotic fibromatosis A nonencapsulated mass on the anterior abdominal wall, most commonly in postpartum ♀, often 2º to trauma which, according to anecdotal reports, may regress with local progesterone injection

des·moid

(des'moyd)
1. Fibrous or ligamentous.
2. A nodule or mass of firm scarlike connective tissue resulting from active proliferation of fibroblasts, occurring most frequently in the abdominal muscles of women who have borne children.
Synonym(s): desmoid tumor.
[desmo- + G. eidos, appearance, form]
References in periodicals archive ?
- The US Food and Drug Administration has granted Breakthrough Therapy Designation for nirogacestat, an oral, selective, small molecule, gamma-secretase inhibitor, for the treatment of adult patients with progressive, unresectable, recurrent or refractory desmoid tumors or deep fibromatosis, US-based biopharmaceutical company SpringWorks Therapeutics, Inc.
Margin-negative resection has historically been the gold standard for treatment of abdominal wall and intra-abdominal desmoid tumours.
The DeFi trial is a global, randomised, double-blind, placebo-controlled Phase three trial to assess the efficacy, safety and tolerability of nirogacestat in adult patients with progressing desmoid tumors.
Histopathology reports were consistent with desmoid tumor with negative surgical margins.
Nirogacestat is an investigational, oral, small molecule, selective gamma-secretase inhibitor used to treat adult patients with progressive, unresectable, recurrent or refractory desmoid tumours or deep fibromatosis.
They said the plaintiff's expert conceded that early removal of the desmoid tumor would not have been different from the ultimate procedure.
Desmoid tumor (DT), also known as aggressive fibromatosis, is a rare entity, representing only 0.03% of all neoplasms in humans.
Desmoid tumors of the head and neck: a therapeutic challenge.
During the definitive diagnosis; lipoma, granuloma, sebaceous cyst, neuroma, hernia, hematoma, lymphadenopathy, lymphoma, desmoid tumors and sarcomas on the abdominal wall must also be considered (2,4,17).
(1,7) It has often been underreported and clinically mistaken for a hernia, suture granuloma, desmoid tumor, nodular fasciitis, lipoma, sarcoma, or metastatic malignancy.
Patients identified in our case series and in the literature review with desmoid tumours, Kaposi sarcoma, and gastrointestinal stromal tumours (GISTs) were excluded from the study due to their unique disease pattern which differs from that of other STSs.