descending necrotising mediastinitis

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descending necrotising mediastinitis

Mediastinitis which arises from a severe infection of the oropharynx.

Diagnostic criteria
• Evidence of severe cervical infection;
• Radiographic features of mediastinitis;
• Documentated necrotising mediastinits at operation or at postmortem;
• Confirmed link between mediastinitis and oropharyngeal infection.

Clinical findings
Fever, chills, pleuritic/retrosternal pain, SOB, confusion, sore throat, neck swelling, odynophagia.
More common in men (6:1) in their 30s.
Other medical complaints including HIV, diabetes, drug abuse and cancer; history of recent iatrogenic procedures, such as endoscopy, bronchoscopy, intubation or surgery.

Mixed infection, with slightly geater abundance of strict anaerobic bacteria, comprised of Bacteroides, the most common strict anaerobes, and streptococci, the most common facultative organisms.

Blood cultures, white cell count, glucose levels to detect diabetes.
Widening of precervical and retropharyngeal soft tissues by plain films; gas by CT or MRI.

Airway maintenance and management; antibiotics, fluid resuscitation.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.
References in periodicals archive ?
Optimal treatment of descending necrotising mediastinitis. Thorax 1997;52(8):702-8.
Descending necrotising mediastinitis. Postgrad Med J 1995;71:98-101.