In a December 21, 2017 medical report, neurologist at the UK's National Hospital for Neurology and Neurosurgery Michael Hanna said Loizou had been evaluated on many occasions and was found to experience significant neurological fatigue, intermittent oxygen desaturations
(reduction in blood oxygen levels) and intermittent respiratory difficulties.
On physical examination, the on-call resident noted intermittent retractions with inspiratory stridor, and the patient demonstrated intermittent severe oxygen desaturations
into the 70s.
Patients with AHI greater than 15.6 events per hour or in the DI4% tertile (more than 9.3 desaturations
per hour) were approximately twice as likely (1.94 and 1.93 times, respectively) to have a more aggressive melanoma as were those with less severe sleep apnea, after adjustment for age, gender, body mass index, and melanoma location.
Severity classification of OSA is based on the frequency and depth/nadir of the desaturations
and the number of desaturation
clusters, defined as periods of desaturation
([greater than or equal to]5 drops [greater than or equal to] 4% from baseline) within a 10-30-minute period (Table 1).
An improvement was observed in both maternal and fetal parameters during the intervention night, with an increase in median minimum maternal oxygen saturation, fewer maternal oxygen desaturations
, and fewer fetal heart rate decelerations.
(13) were reported that the frequency of nocturnal desaturation
was significantly higher and the duration of desaturations
was longer in the printers than in the controls.
We suggest that ODI, an indicator of the number of oxygen desaturations
developing together with apnea and hypopnea during sleep, can be a significant parameter in addition to AHI for the diagnosis of OSA.
At the time of discharge a "car seat test" is performed but the reliability of this to predict desaturations
in a simulated car ride has been questioned .
The oxistimulator, developed by clinical practitioners at the Department of Anesthesiology at Mayo Clinic, is a new, non-invasive technology that aims to prevent post-operative desaturations
complications by providing timely, peripheral tactile stimulation whenever clinically defined desaturations
The baseline mean Sp[O.sub.2] improved to 95% and there were significantly fewer desaturations
throughout the night (desaturation
index = 0.5/hr).
Repeated oxygen desaturations
, single snoring, brady- and tachyarrhythmias, and arousals were associated with apneic episodes.