desaturase


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desaturase

(dē-sach′ŭ-rās″) [ de- + satur(ate) + -ase]
An enzyme that converts an unsaturated fatty acid chain to one that includes at least one carbon-carbon double bond.

desaturase

an enzyme capable of catalyzing desaturation of fatty acids.
References in periodicals archive ?
We propose that supplementation in Groups IV and V increased I9- desaturase capacity via stimulation of stearoyl-CoA desaturase mRNA expression in the SAT.
n-3 LC-PUFAs decrease liver steatosis by decreasing the expression of delta 9 desaturase enzymes, lipogenesis and stimulating fatty acid oxidation in the liver (Parker et al.
The following indices were also calculated: A9 desaturase 16 = 100 [(C16: 1cis9)/(C16 + C16 1cis9: 0)]; A9 desaturase 18 = 100 [(C18: 1cis9)/(C18: 1cis9 + C18: 0)]; elongase = 100 [(C18: 0 + C18: 1cis9)/(C16: 0 + C16: 1cis9 + C18: 0 + C18: 1cis9)]; atherogenicity = [C12: 0 + 4 (C14: 0) + C16: 0]/([summation]SFA [summation]PUFAI + [summation]MUFA)]; and thrombogenicity = [(C14: 0 + C16: 0 + C18: 0)/[(0.
ABSTRACT The synthesis of highly unsaturated fatty acids (HUFAs) from C18 fatty acids in the Pacific white shrimp, Litopenaeus vannamei, has long been debated in terms of the limited capacity or even the existence of fatty acid desaturase and elongase.
Previous investigations have confirmed that, desaturation of oleic acid (18C:1) to linoleic acid (18C:2) or linolenate acid (18C:3) is catalyzed by fatty acid desaturase 2 (FAD2) and FAD3, respectively (Sperling and Heinz,1993; Okuley et al.
In mammalians, delta 5 desaturase and delta 6 desaturase enzymes synthesize the polyunsaturated fatty acids from linoleic, linolenic and oleic acids [49-51].
Expression and nutritional regulation of stearoyl-CoA desaturase genes in the ruminant mammary gland: Relationship with milk fatty acid composition.
11,12,13) Short chain EFA-Omega (6) (Linoleic Acid) and Omega 3 (Alpha linolenic acid) with the help of enzymes desaturase and elongase are converted to Long Chain Fatty Acids, AAArachidonic Acid, GLA-Gamma linolenic acid, DGLA-DihomoGLA, EPA-Eicosapentaenoic Acid, DHA- Docosahexaenoic Acid which are further converted to eicosanoids (PGProstaglandins, PGI-Prostacyclins, TX-Thromboxane by the enzyme Cyclooxygenase and LT-Leukotrienes by the enzyme15-Lypoxygenase).
The TaqMan primer/probe sets for FASN (Hs01005622_ml), acetyl-CoA carboxylase [alpha] (ACACA, Hs01046047_ml), sterol regulatory element binding transcription factor 1 (SREBF1, Hs01088691_ml), stearoyl-CoA desaturase (SCD, Hs01682761_ml), nuclear receptor subfamily 1, group H, member (NR1H) 3 (LXR-[alpha], Hs00172885_ml), NR1H2 (LXR-[beta], Hs01027215_gl), RXR-[alpha] (Hs01067640_ml), and actin, beta (ACTS, Hs01060665_gl) were purchased from Applied Biosystems (CA, USA).
Age-related changes in delta 6 and delta 5 desaturase activities in rat liver microsomes.
Mammalian cells are short of the desaturase that can convert n-6 to n-3 PUFAs, which means that n-3 PUFAs must be supplied with the diet.

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