dermatofibrosis

dermatofibrosis

a syndrome inherited as a dominant trait in German shepherd dogs in which multiple, firm cutaneous and subcutaneous nodules of mature fibrous tissue, up to 2 inches in diameter, develop in middle age. Affected animals show a high incidence of renal adenocarcinoma and females have multiple uterine and vaginal leiomyomas. Called also nodular dermatofibrosis.
References in periodicals archive ?
Disseminated dermatofibrosis with osteopoikilosis).
Frequently, the disease is associated with dermatological disorders like: disseminated lenticular dermatofibrosis, keloid or discoid lupus and similar lesions to scleroderma [13, 14, 19, 20, 30].
Generalized Nodular Dermatofibrosis in Six Alsatians.
Hereditary multifocal renal cystadenocarcinomas and nodular dermatofibrosis in the German Shepherd dog: macroscopic and histopathologic changes.
Various developmental malformations have been reported to be associated with osteopoikilosis, including: coarctation of the aorta, double ureter, pubertas praecox, urogenital defects, growth abnormalities, peptic ulcer, diabetes mellitus at the endodermal strata level; arthritis, exostoses, osteitis condensans ilii, Klippel-Feil Syndrome, melorheostosis, spinal stenosis, cervical myelopathy, dacryocystitis, giant cell tumor, fibrous dysplasia, chondrosarcoma, osteosarcoma, synovial chondromatosis at the mesodermal level; facial abnormalities, hare lip, dental abnormalities, dermatofibrosis lenticularis disseminata, keloid formation, plantar and palmar keratomas at the ectodermal level (14-16).
1,2) Several clinical abnormalities associated with OPK have been reported, including rheumatoid arthritis, synovial chondromatosis, and, more frequently, dermatological pathologies (such as dermatofibrosis lenticularis disseminata, keloid formations and scleroderma-like lesions).
Dermatofibrosis lenticularis disseminata and osteopoikilosis [in German].
Nodular dermatofibrosis, also known as multiple CN (SCOTT et al.
In this case, the diagnosis of nodular dermatofibrosis (Figure 1C) associated to unilateral papillary cystadenoma was confirmed.
Generalized nodular dermatofibrosis and renal cystadenocarcinomas in a German Shepherd Dog.
Generalised nodular dermatofibrosis and renal cystadenoma in a series of 10 closely related German Shepherd Dogs.