dermatofibrosarcoma protuberans


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der·mat·o·fi·bro·sar·co·ma pro·tu·ber·ans

(der'mă-tō-fī'brō-sar-kō'mă prō-tū'bĕr-anz),
A relatively slowly growing dermal neoplasm consisting of one or several firm nodules that are usually covered by dark red-blue skin, which tends to be fixed to the palpable masses; histologically, the neoplasm resembles a cellular dermatofibroma with a pronounced storiform pattern; metastases are unusual, but the incidence of recurrence is fairly high.

der·mat·o·fi·bro·sar·co·ma pro·tu·ber·ans

(dĕr'mă-tō-fī'brō-sahr-kō'mă prō-tū'bĕr-anz)
Dermal neoplasm consisting of one or several firm nodules covered by dark red-blue skin, which tends to be fixed to the palpable masses; histologically, resembles a cellular dermatofibroma with a pronounced storiform pattern; metastases are unusual, but the incidence of recurrence is fairly high.
References in periodicals archive ?
Dermatofibrosarcoma protuberans. J Am Acad Dermatol 1996;35(3 Pt 1):355-74, quiz 3756.
Dermatofibrosarcoma protuberans: a comprehensive review and update on diagnosis and management.
Spagnoli, "Myxoid dermatofibrosarcoma protuberans: Morphological, ultrastructural and immunohistochemical features," Journal of Cutaneous Pathology, vol.
Camarco et al., "Dermatofibrosarcoma protuberans of the vulva: Margins assessment and reconstructive options--A report of two cases," World Journal of Surgical Oncology, vol.
Dermatofibrosarcoma protuberans (DFSP) is a locally aggressive soft tissue neoplasm with intermediate malignant potential, regarded as a low grade sarcoma by the WHO classification of tumours of the skin.
A clinical diagnosis of dermatofibrosarcoma protuberans was made.
Dermatofibrosarcoma protuberans (DFSP) is a rare dermal malignancy affecting the deep dermis and subcutaneous tissues.
(3-9) Clinical differential diagnosis includes the nodular variant of chromoblastomycosis, keloids, xanthomas, fibromas, Kaposi's sarcoma, neurofibromas and dermatofibrosarcoma protuberans. Differentiation of keloidiform lesions on the ears from lepromatous leprosy is difficult, but the unilaterality is characteristic of lobomycosis.
It differs from other fibrous conditions such as fibromatosis, juvenile aponeurotic fibroma, subepidermal nodular fibrosis, and dermatofibrosarcoma protuberans. (6) The histologic differential diagnosis includes benign tumors such as fibrous histiocytomas, pyogenic granulomas, peripheral nerve sheath tumors, and cutaneous smooth-muscle tumors.
Diferenciar con Fibroma, Queloide, Tumor fibroso recurrente de la infancia, Dermatofibrosarcoma protuberans, Dedos supranumerarios, cuerno cutaneo o verruga vulgar, Fibroqueratoma periungueal adquirido fibromatosis digital infantil, poroma ecrino, granuloma piogenico.
A chest computed tomography scan is routinely used to look for metastases, but it is not appropriate in sarcomas that rarely metastasise, such as dermatofibrosarcoma protuberans (DFSP).
FNAC of dermatofibrosarcoma protuberans cases showed scanty to moderate cellularity, consisting of small cohesive clusters of short spindle cells and a diagnosis of BML was given.