dermatofibroma


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dermatofibroma

 [der″mah-to-fi-bro´mah]
a fibrous tumorlike nodule of the skin, usually on the extremities and especially the legs. Its etiology is not known, but it is most likely a neoplastic disorder. Although it is benign, itching and pain can be a source of severe discomfort.

der·ma·to·fi·bro·ma

(der'mă'tō-fī-brō'mă),
A slowly growing benign skin nodule consisting of poorly demarcated cellular fibrous tissue enclosing collapsed capillaries, with scattered hemosiderin-pigmented and lipid macrophages. The following terms are considered by some to be synonymous with, and by others to be varieties of, dermatofibroma: sclerosing hemangioma (2), fibrous histiocytoma, nodular subepidermal fibrosis.

dermatofibroma

[dur′mətōfībrō′mə] pl. dermatofibromas, dermatofibromata
Etymology: Gk, derma + L, fibra, fiber, oma, tumor
a cutaneous nodule that is painless, round, firm, gray or red, elevated, and commonly found on the extremities. No treatment is required. Also called fibrous histiocytoma.

benign fibrous histiocytoma

A benign tumour composed of primitive mesenchymal cells (macrophages or histiocytes) seen in the skin and soft tissues of the legs of young to middle-aged patients, more commonly women, usually in relation to skeletal muscle.
 
Management
Excision.

der·ma·to·fi·bro·ma

(dĕr'mă-tō-fī-brō'mă)
A slowly growing benign skin nodule consisting of poorly demarcated cellular fibrous tissue enclosing collapsed capillaries, with scattered hemosiderin-pigmented and lipid macrophages. The following terms are considered by some to be synonymous with, and by others to be varieties of, dermatofibroma: sclerosing hemangioma, fibrous histiocytoma, nodular subepidermal fibrosis.
Enlarge picture
DERMATOFIBROMA
Enlarge picture
DERMATOFIBROMA

dermatofibroma

(der?ma-to-fi-bro'ma) [? + L. fibra, fiber, + Gr. oma, tumor]
A firm but freely movable benign skin nodule, often found on the lower extremities.
See: illustration; dimple signillustration

dermatofibroma

; histiocytoma cutis; fibrous histiocytoma sclerosing haemangioma: common benign fibroma of extremities; flat/slightly raised flesh-coloured/yellowish-brown, firm/hard, non-progressive, isolated lesions usually <1 cm in diameter; palpable bulk of lesion extends beyond its visible outline

dermatofibroma

a fibrous tumor-like nodule of the skin.
References in periodicals archive ?
Spectrum of follicular and sebaceous differentiation induced by dermatofibroma.
CD34 and factor-XIIIa immunoreactivity in dermatofibrosarcoma protuberans and dermatofibroma.
Dermatofibroma on upper extremity in childhood period.
CHICAGO -- A seemingly benign skin lesion that initially presented as a possible dermatofibroma turned out to be an unusual amelanotic melanoma, Sarvenaz Zand reported in a poster at the annual meeting of the American Society of Dermatopathology.
3 Pancreatic ductal carcinoma 0/21 0 Pancreatic adenocarcinoma 0/25 0 Pheochromocytoma 0/5 0 Prostate adenocarcinoma 0/38 0 Renal cell carcinoma 0/37 0 Bone and soft tissue tumors (n = 84) Bone (giant cell tumor) 0/11 0 Osteosarcoma 0/5 0 Liposarcoma 0/15 0 Fibrosarcoma 0/20 0 Dermatofibroma protuberans 0/3 0 Sarcoma unclassified 0/4 0 Rhabdomyosarcoma 0/10 0 Leiomyosarcoma 0/9 0 Epithelioid sarcoma 0/2 0 Synovial sarcoma 0/3 0 Carcinosarcoma 0/1 0 Angiosarcoma 0/1 0 Seminoma 0/70 0 Thymic tumors (n = 14) Thymic carcinoma 5/12 41.
Many lesions like Dermatofibroma, Epidermal inclusion cyst, Keloid, Hypertrophic scars, Malignant Melanoma and metastatic carcinoma come in the differential diagnosis of DFSP.
Atypical fibrous histiocytoma is the atypical variant of dermatofibroma (fibrous histiocytoma).
Clinical differential diagnosis includes basal cell and squamous cell carcinoma, melanoma, metastatic tumor, dermatofibroma, pyogenic granulomas, hemangioma, leiomyoma and other cutaneous adnexal tumors.
There is little documentation of similar lesions in the literature before this perhaps because these were subsumed into descriptions of other entities such as sclerosing hemangioma, (2) dermatofibroma, and other lesions classified as fibrous histiocytoma.