Tobacman, "Molecular signature of kappa-carrageenan mimics chondroitin-4-sulfate and dermatan sulfate
and enables interaction with arylsulfatase B," Journal of Nutritional Biochemistry, vol.
Functionally, [alpha]-L-iduronidase is essential to the correct metabolism of both dermatan sulfate
and of heparan sulfate (2, 9), hydrolyzing the terminal [alpha]-L-iduronic acid residues.
Studies have also shown that fibroids and myometrium possess different percentages of the glycosaminoglycans chondroitin sulfate and dermatan sulfate
as there is 78% in myometrium and 95% in fibroids (as discussed in ).
Pronuclear status of bovine zygotes 18 h after IVF using GAG-treated sperm Treatment * Number Fertilization (%) examined 2 PN (%) Control 64 38 (59.4) (a) DS 64 37 (57.8) (a) CS 64 40 (62.5) (a) HA 64 46 (71.9) (ab) HP 64 52 (81.3) (b) Treatment * Fertilization (%) Polyspermy Total Multi PN 2 PN+sperm SUM Control 6 (9.4) 5 (7.8) 11 (17.2) 49 (76.6) DS 8 (12.5) 2 (3.1) 10 (15.6) 47 (73.4) CS 3 (4.7) 2 (3.1) 5 (7.8) 45 (70.3) HA 5 (7.8) -- 5 (7.8) 51 (79.7) HP 4 (6.3) -- 4 (6.3) 56 (87.6) * DS: dermatan sulfate
; CS = Chondroitin sulfate; HA = Hyaluronic acid; HP = Heparin.
Simultaneous detection of submicrogram quantities of hyaluronic acid and dermatan sulfate
on agarose gel by sequential staining with toluidine blue and Stains-All.
(2000) Enzymatic reconstruction of dermatan sulfate
Other examples of glycosaminoglycans in the human body include chondroitin sulfates, ketatan sulfate, heparin, heparan sulfate, and dermatan sulfate
. Hyaluranon's function is to help form the extracellular matrix that supports and protects cells.
Candidate polysaccharide or proteoglycan subunits include aggrecan, agrin, bamacan, heparan sulfate, chondroitin sulfate, keratan sulfate, versican, phosphocan, perlecan, hyaluronan, decorin, dermatan sulfate
, biglycan, fibromodulin, alginate, polylactate, polyglycolic acid, starch, dextran, agarose, chitan, chitosan, and heparin.
Danaparoid is derived from porcine intestinal mucosa containing 84% heparin sulfate, dermatan sulfate
, and chondroitin sulfate.
The lysosomes in the cells of children with Hurler syndrome do not have a vital enzyme called IDUA (/a-/L-idunronidase), which causes their cells to accumulate too much of a class of biochemical known as mucopolysaccharides, in this instance dermatan sulfate
and heparin sulfate.
Eggshell membranes contain fibrous proteins such as collagen, but have also been shown to contain glycosaminoglycans (GAGs) such as dermatan sulfate
and chondroitin sulfate, hexosamines such as glucosamine, and significant amounts of hyaluronic acid, all important ingredients in joint care.