dermatan sulfate


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der·ma·tan sul·fate

an anticoagulant with properties similar to those of heparin and sharing with heparin a sulfated mucopolysaccharide structure; a repeating polymer of l-iduronic acid and N-acetyl-d-galactosamine. O-Sulfation of iduronic acid residues at the C-2 position and of galactosamine residues at the C-4 and C-6 positions occurs to a variable extent.

dermatan sulfate

(dûr′mə-tăn′)
n.
A glycosaminoglycan that is a structural component of certain body tissues, especially the skin.

der·ma·tan sul·fate

(dĕrmă-tan sŭlfāt)
Anticoagulant with properties similar to those of heparin.

dermatan sulfate

a component of the acellular ground substance of skin.
References in periodicals archive ?
The largest proportion of urinary GAG is chondroitin sulfate (62%-77%), whereas heparan sulfate accounts for ~25% and dermatan sulfate for only ~5% (214).
It may require dedicated methods to measure urinary GAG subspecies to detect defects of heparan sulfate and dermatan sulfate biosynthesis.
It is also referred to as dermatan sulfate, and is made up of linear repeating units containing D-galactosamine and either L-iduronic acid or D-glucuronic acid.
Mucopolysaccharidosis I (MPS I) is characterized by the deficiency of alpha-L-iduronidase, a lysosomal hydrolase which catalyses the hydrolysis of terminal alpha-L-iduronic acid residues of dermatan sulfate and heparan sulfate.
Furthermore, the presence of dermatan sulfate was excluded.
Fast moving" and "slow moving" heparins, dermatan sulfate, and chondroitin sulfate: qualitative and quantitative analysis by agarose-gel electrophoresis.
Although the heparan sulfate subfraction was higher in hypertensive patients compared with the normotensive group, the dermatan sulfate subfraction of GAG was higher in the normotensives.
Effects of unfractionated heparin, dermatan sulfate and low molecular weight heparin on vessel wall permeability in rabbits.
Armand began his career at the University of Chicago in the early 1960's where he was involved in the isolation and structural characterization of heparan sulfate and dermatan sulfate from skin fibroblasts and from urine derived from patients with "Hurler Syndrome ", a form of mucopolysaccharidoses.
These disorders all store either heparan sulfate, dermatan sulfate, keratan sulfate, or a combination of these.