Sayed et al., "Downregulation of MiR-199a derepresses
hypoxia-inducible factor-1[alpha] and sirtuin 1 and recapitulates hypoxia preconditioning in cardiac myocytes," Circulation Research, vol.
(10) The RB gene product represses expression of cyclin-dependent kinase inhibitor 2A (p16), so the effects of E7 expression on RB derepresses
p16 expression, a slide-based marker also associated with cancer and its precursors.
To explain this phenomenon Steen and Collas have suggested the presence of a signaling mechanism that derepresses
the LMNA gene in response to a mislocalization of lamin B at the end of mitosis.
The third position introduced by Freud at once derepresses
the existence of childhood sexuality and emphasizes the importance of aim-inhibited libidinal ties, especially during the "return" of sexuality in early adolescence.
These results reveal that H19 competitively binds to miR-200a and derepresses
[beta]-catenin expression in CRC.