deprenyl


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Related to deprenyl: L-deprenyl, Hydergine

de·pre·nyl

(dē'pren-il),
A noncompetitive inhibitor of monoamine oxidase selective for the type B isozyme, which is responsible for oxidative deamination of dopamine in the brain. The drug is used as an antiparkinsonian agent.
Synonym(s): deprenil
Farlex Partner Medical Dictionary © Farlex 2012

deprenyl

Alternative pharmacology
A prescription drug used to treat Parkinson’s disease, which has acquired currency among some practitioners of alternative medicine as an anti-ageing substance; deprenyl acts on the substantia nigra., a region of the brain that is believed to age more rapidly than others, by blocking the degradation of dopaminergic neurotransmitters.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.

deprenyl

Eldepryl, selegiline A selective irreversible inhibitor of type B monoamine oxidase that delays the onset of disability in Pts with early untreated Parkinson's disease–PD. See MPTP.
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.
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References in periodicals archive ?
The dichloromethane extract (0.001 to 100 [micro]g/mL), purified compounds ([10.sup.-9] to [10.sup.-2] M), and standard MAO inhibitors (phenelzine, clorgyline, and deprenyl) ([10.sup.-12] to [10.sup.-5] M) were tested on human MAOA and MAO-B enzymes [19].
Interactions of Desmethoxyyangonin, a Secondary Metabolite from Renealmia alpinia, with Human Monoamine Oxidase-A and Oxidase-B
The Deprenyl and Tocopherol Antioxidative Therapy of Parkinsonism (DATATOP) study was designed to investigate the potential for selegiline to modify the disease course in early PD.
The management of Parkinson's disease: in the primary care setting
Increased effectiveness of tacrine by deprenyl co-treatment in rats: EEG and behavioural evidence.
Alteration of brain monoamines & EEG wave pattern in rat model of Alzheimer's disease & protection by Moringa oleifera
Exogenous analogues of these compounds are antidepressants such as pargyline, deprenyl, and so on.
An immunochemical approach to model and long-term suppression of depressive and anxiety behavior
Although 100 mg/kg gentamicin (sc) led to nephrotoxicity at 24 hr, no hepatotoxicity was associated with it, nor was hepatotoxicity detected with deprenyl or lazabemide.
Discriminating different classes of toxicants by transcript profiling
Serotonin syndrome and the combined use of deprenyl and an antidepressant in Parkinson Es disease.
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Formerly Deprenyl Research Ltd., Draxis Health is engaged
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(Mirapex) Anticholinergics, amantadine and deprenyl Trihexyphenidyl (Artane) May help reduce tremor and to a Apo-trihex lesser extent, bradykinesia and Benztropine (Cogentin) rigidity.
Nursing care of patients with late-stage Parkinson's disease
Deprenyl, a monoamine oxidase B inhibitor is known to upregulate activities of antioxidant enzymes such as superoxide dismutase and catalase in brain's dopaminergie regions.
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Meanwhile, ambitious men in the US are increasingly turning to ``smart'' drugs like Deprenyl, which enhances so-called lifestyle characteristics like aggressiveness, territoriality, accomplishment, sexuality and achievement.
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Determination of enantiomeric metabolites of L-deprenyl, o-methamphetamine, and racemic methamphetamine in urine by capillary electrophoresis: comparison of deprenyl use and methamphetamine use.
Drug testing in blood: validated negative-ion chemical ionization gas chromatographic-mass spectrometric assay for determination of amphetamine and methamphetamine enantiomers and its application to toxicology cases

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