deprenyl


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Related to deprenyl: L-deprenyl, Hydergine

de·pre·nyl

(dē'pren-il),
A noncompetitive inhibitor of monoamine oxidase selective for the type B isozyme, which is responsible for oxidative deamination of dopamine in the brain. The drug is used as an antiparkinsonian agent.
Synonym(s): deprenil

deprenyl

Alternative pharmacology
A prescription drug used to treat Parkinson’s disease, which has acquired currency among some practitioners of alternative medicine as an anti-ageing substance; deprenyl acts on the substantia nigra., a region of the brain that is believed to age more rapidly than others, by blocking the degradation of dopaminergic neurotransmitters.

deprenyl

Eldepryl, selegiline A selective irreversible inhibitor of type B monoamine oxidase that delays the onset of disability in Pts with early untreated Parkinson's disease–PD. See MPTP.
References in periodicals archive ?
2 Aged dogs given deprenyl had twice the survival rate compared with placebo-treated dogs.
Effects of tocopherol and deprenyl on the progression of disability in early Parkinson's disease.
Exogenous analogues of these compounds are antidepressants such as pargyline, deprenyl, and so on.
No menciona el Deprenyl, la bromocriptina, la L-dopa etc.
Although 100 mg/kg gentamicin (sc) led to nephrotoxicity at 24 hr, no hepatotoxicity was associated with it, nor was hepatotoxicity detected with deprenyl or lazabemide.
Serotonin syndrome and the combined use of deprenyl and an antidepressant in Parkinson Es disease.
Mirapex) Anticholinergics, amantadine and deprenyl Trihexyphenidyl (Artane) May help reduce tremor and to a Apo-trihex lesser extent, bradykinesia and Benztropine (Cogentin) rigidity.
The use of monoamine oxidase B inhibitors that have biochemical mechanisms similar to Deprenyl may provide new topical anti-aging strategies.
Meanwhile, ambitious men in the US are increasingly turning to ``smart'' drugs like Deprenyl, which enhances so-called lifestyle characteristics like aggressiveness, territoriality, accomplishment, sexuality and achievement.
Determination of enantiomeric metabolites of L-deprenyl, o-methamphetamine, and racemic methamphetamine in urine by capillary electrophoresis: comparison of deprenyl use and methamphetamine use.
org/) In the US, you can't get deprenyl, a drug for treating Parkinson's disease, available only on prescription, but sold freely in Europe.
Over time the Sinemet lost its effectiveness, so his doctor added Deprenyl to inhibit further dopamine breakdown.