depolarizing relaxant

de·po·lar·iz·ing re·lax·ant

an agent for example, succinylcholine) that induces depolarization of the motor endplate and so paralyzes skeletal muscle by a phase I block.
Farlex Partner Medical Dictionary © Farlex 2012
References in periodicals archive ?
To the Editor: Malignant hyperthermia (MH) is a rare but potentially fatal, inherited skeletal muscle disorder that is mostly induced by the ingestion of the depolarizing relaxant, i.e., succinylcholine or volatile anesthetics.[sup][1] Its incidence is reportedly 1/5000 to 1/100,000 in general anesthesia patients, and children seem to be more susceptible than adults.[sup][2] According to MH treatment guidelines of the Malignant Hyperthermia Association of the United States (MHAUS) and European Malignant Hyperthermia Group (EMHG), dantrolene should be administered as soon as possible in suspected case.[sup][3],[4] Unfortunately, dantrolene is not readily available worldwide.
In Britain, Cyril Scurr began experimenting with another depolarizing relaxant created by Bovet--suxethonium.