A total of 50 patients were enrolled in the study, which included 250 sites of depigmentation
for autologous Non-Culture Melanocyte-Keratinocyte Transfer (NCMT) and 125 sites for punch grafting.
Treatment with high-potency topical steroids, calcineurin inhibitors, or both resulted in improvement or resolution of their symptoms in all cases, but there was mild or no improvement in the depigmentation
. Biopsies were not performed because of the patients' young age and the location of the lesions, they said (Pediatr Dermatol.
Current topical treatment options include camouflage, cosmetics, sunscreens, topical corticosteroids, vitamin D analogues, topical calcineurin inhibitors, and depigmentation
The authors defined MAL as "depigmentation
that developed within 1 year before the detection of a primary melanoma or within 3 years before the detection of melanoma metastases with an unknown primary tumour."
Since no acknowledged treatment modality is available to cure vitiligo, numerous methods such as Cosmetics for concealment, Systemic phototherapy using UV light for repigmentation, Steroid therapy--systemic (prednisone) or corticosteroid creams, Depigmentation
of unaffected skin parts, Micropigmentation (tattooing in dark-skinned individuals--works best for the lip area) and LASERs (Excimer laser), can be used for facade betterment of skin affected by vitiligo.
The successful development of a skin whitening formulation incorporates two plausible approaches to skin depigmentation
based on this mechanism of melanin formation: the inhibition of melanin biosynthesis, and possible conversion of melanin and its colored precursors (dopachrome, leucochrome) into colorless entities.
Sex massage oil, postinflammatory depigmentation
, chronic Irritant dermatitis.
It is also known as skin depigmentation
. In skin depigmentation
, the skin's pigment-making cells known as melanocytes are lost or destroyed, which result into patches.
MEHQ is the main ingredient in topical drugs which are used for skin depigmentation
. The drug is commonly formulated by the addition of an ethanolic solution of 2% MEHQ and 0.01% of tretinoin by mass.
MILAN -- Targeting the Janus kinase (JAK) 1 and 2 pathways in vitiligo resulted in significant reduction of facial depigmentation
after 24 weeks of treatment, in a phase 2b trial of topical ruxolitinib cream.
A rare side effect is the immune system indiscriminately going after a dog's normal pigment cells as well as the cancer cells leading to depigmentation
or a graying of the coat.
Vitiligo is an autoimmune skin disease which can be identified by skin depigmentation
due to the destruction of melanin cells in the body due to which skin loses its original color, and white spots occur.