deoxyribozyme


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deoxyribozyme

(dē-ŏk″sē-rī′bō-zīm))
A DNA molecule capable of cleaving itself (i.e., of cutting itself into smaller pieces).
References in periodicals archive ?
Folding of 8-17 deoxyribozyme studied by three-color alternating-laser excitation of single molecules.
Four-color alternating-laser excitation single-molecule fluorescence spectroscopy for next-generation biodetection assays
Factors that influence deoxyribozyme cleavage during polymerase chain reaction.
Diagnosis and molecular monitoring of acute promyelocytic leukemia using DzyNA reverse transcription-PCR to quantify PML/RAR[alpha] fusion transcripts
The deoxyribozymes will provide a means of synthesizing (ligating) large amounts of RNA in hours at 37[degrees]C.
The deoxyribozymes require the RNA junction ligation termini to be a 2'-3' cyclic phosphate and a 5' hydroxyl group.
New Jersey Academy of Science and Affiliated Societies program of the 48th annual meeting
Functionally, these deoxyribozymes are cousins of protein enzymes known as restriction endonucleases.
DNA scissors cleave their comrades
Although the activity of the described oligonucleotides is weak, these deoxyribozymes could be further optimized to enhance their catalytic power, making them valuable for diagnostic applications.
Aptamers: an emerging class of molecules that rival antibodies in diagnostics
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