The radical formed from deoxyribose by removal of the OH from the C-1 carbon, for example, deoxyadenosine. Compare: deoxyriboside.
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They can also cause damage to the nuclear DNA by altering the chemical structure of the nucleotide bases and the deoxyribosyl backbone (Cooke et al., 2003).
All ROS have the potential to interact with cellular components including DNA bases or the deoxyribosyl backbone of DNA to produce damaged bases or strand breaks.