deoxyribonuclease


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Related to deoxyribonuclease: Deoxyribonucleic

deoxyribonuclease

 (DNase) [de-ok″sĭ-ri″bo-nu´kle-ās]
an enzyme that catalyzes the hydrolysis (depolymerization) of deoxyribonucleic acid (DNA).
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

de·ox·y·ri·bo·nu·cle·ase (DNAse, DNAase, DNase),

(de-oks'ē-rī'bō-nū'klē-ās),
Any enzyme (phosphodiesterase) hydrolyzing phosphodiester bonds in DNA.
See also: endonuclease, nuclease.
Farlex Partner Medical Dictionary © Farlex 2012

deoxyribonuclease

(dē-ŏk′sē-rī′bō-no͞o′klē-ās′, -āz′, -nyo͞o′-)
n.
DNase.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.

APEX1

A gene on chromosome 14q11.2 that encodes a major apurinic/apyrimidinic (AP) endoDNAase, which is involved in the DNA base excision repair (BER) pathway of DNA lesions induced by oxidative and alkylating agents, and in the redox regulation of transcriptional factors.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.

de·ox·y·ri·bo·nu·cle·ase

(DNase) (de-oks'ē-rī'bō-nū'klē-ās)
Any enzyme (phosphodiesterase) hydrolyzing phosphodiester bonds in DNA.
See also: endonuclease, nuclease
Medical Dictionary for the Health Professions and Nursing © Farlex 2012

deoxyribonuclease

An enzyme that cuts DNA strands by breaking PHOSPHODIESTER BONDS.
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005

deoxyribonuclease (DNAse)

see NUCLEASE.
Collins Dictionary of Biology, 3rd ed. © W. G. Hale, V. A. Saunders, J. P. Margham 2005
References in periodicals archive ?
[35.] Lazarus RA, Wagener JS (2007) Recombinant Human Deoxyribonuclease I".
Typical colonies (black surrounded by clear zones) were tested for coagulase activity using rabbit plasma after activation by overnight incubation in Brain Heart broth, at 35[degrees]C, and tested for deoxyribonuclease (DNAse) activities by using DNAse agar, and revealed by hydrochloric acid (HCl) at 2%.
Selective media such as mannitol salt agar and deoxyribonuclease (DNase) agar can differentiate the species of Staphylococcus.
On January 9, 2007, ASVL sent the unidentified viral isolate to CDC, where the isolate was evaluated using two pathogen-discovery strategies: a pan-herpes virus polymerase chain reaction (PCR) test and a deoxyribonuclease sequence-independent, single-primer amplification (DNase-SISPA) sequencing method, * in which a specimen is treated with DNase, followed by nucleic acid extraction, random amplification, restriction enzyme digestion, and SISPA of the restriction fragments.
Although serologies in most patients were positive for both antistreptolysin O and deoxyribonuclease B antibodies, indicating [beta]-hemolytic streptococci infection, some were positive for just one or the other antibody.
Although serologies in most patients were positive for both antistreptolysin O and deoxyribonuclease B antibodies, indicating [beta]hemolytic streptococci infection, some were positive for just one or the other antibody.
There were sufficient data to reject--or at least doubt--the efficacy of several commonly used treatments: aerosolized ribavirin, antibiotics, nebulized furosemide, intravenous RSV immunoglobulin (RSV IG) used for treatment rather than prophylaxis, inhaled interferon-a, and nebulized recombinant human deoxyribonuclease.
1) Deoxyribonuclease (DNase I) sensitive perinuclear antineutrophil cytoplasmic autoantibody (pANCA) associated with IBD.
Heat resistance and other characteristics of deoxyribonuclease positive Enterococci isolated from milk and milk products.
In the second tube, cells were labelled for surface marker CD3 with PE conjugated MoAb followed bydeoxyribonucleic acid (DNA) digestion using deoxyribonuclease (DNase).

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