deoxyguanosine


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de·ox·y·gua·no·sine

(dē-oks'ē-gwahn'ō-sēn),
2'-Deoxyribosylguanine, one of the four major nucleosides of DNA (the others being deoxyadenosine, deoxycytidine, and thymidine). Found to accumulate in individuals with purine nucleoside phosphorylase deficiency.

de·ox·y·gua·no·sine

(dē-oks'ē-gwahn'ō-sēn)
One of the four major nucleosides of DNA (the others being deoxyadenosine, deoxycytidine, and thymidine). Found to accumulate in patients with purine nucleoside phosphorylase deficiency.
References in periodicals archive ?
The focus of this research was to study 2-hydroxy-1,4-dioxane, a by-product of [alpha]-hydroxy-N-nitrosomorpholine, and to determine its effect on deoxyguanosine (dG).
Clinical and molecular features of mitochondrial DNA depletion due to mutations in deoxyguanosine kinase.
For example, the first G peak is twice as tall as the first T peak, indicating that 2 consecutive deoxyguanosine triphosphates (underlined) were incorporated, whereas only one deoxythymidine triphosphate (underlined) was incorporated; 1X and 2X lines represent peak heights because of single or double base incorporation events, respectively.
the formation of 8-hydroxy-2'- deoxyguanosine (8-OHdG), the most studied form of base modification, can be quantified using specific antibody by enzyme-linked immunosorbent assay.
8-OHdG is a by-product from damaged DNA when it is attacked by hydroxyl free radicals at deoxyguanosine in DNA (Park and Floyd 1992).
8-OHdG: (8-oxo-2'-deoxyguanosine) is an oxidized derivative of deoxyguanosine.
Lymphocyte-selective cytostatic and immunosuppressive effects of mycophenolic acid in vitro: role of deoxyguanosine nucleotide depletion.
5mM magnesium chloride, 200 [micro]M each of deoxynucleoside triphosphates (deoxyadenosine triphosphate, deoxycytidine triphosphate, deoxyguanosine triphosphate, and deoxythymidine triphosphate), 0.
Under healthy physiological conditions, the role of dCK is the phosphorylation of deoxycytidine, deoxyadenine, and deoxyguanosine to their monophosphate forms.
5 mmol/L magnesium chloride (Perkin-Elmer); 200 pmol/L each of deoxyadenosine triphosphate, deoxycytidine triphosphate, deoxyguanosine triphosphate, and deoxythymidine triphosphate (Sigma); 200 pmol of each primer; and 10 [micro]L of the extracted DNA sample.
Moreover, oxidative markers, leukocyte 8-hydroxy-2'- deoxyguanosine and lipid hydroperoxides, are detected in association with long-term and short-term clinical outcomes, respectively, after spontaneous ICH [15, 16].
Furthermore, a previous study suggested that artifactual oxidation of deoxyguanosine can occur during sample preparation (33).