dense bodies


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dense bodies

granules in the central granulomere of blood platelets that take up and store serotonin from plasma. Electron-dense bodies containing α-actinin in the cytoplasm of smooth muscle cells associated with the cell membrane are believed to be homologous to the Z-lines of striated muscle.
Farlex Partner Medical Dictionary © Farlex 2012

dense granule

Cardiology
A specialised spherical storage and secretory vesicle in platelets which contains ADP, ATP, ionised calcium, pyrophosphate and serotonin. Reduced-platelet dense-granule secretion is associated with marked protection against arterial thrombosis, inflammation, and neointimal hyperplasia after vascular injury in a mouse model.

Pathology
Dense-core granules, see there.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.

dense bod·ies

(dens bŏd'ēz)
1. Granules in the central granulomere of blood platelets that take up and store serotonin from plasma.
2. Electron-dense bodies containing α-actinin in the cytoplasm of smooth muscle cells, believed to be homologous to the Z-lines of striated muscle.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012
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However, in the DM and DM + SGES groups (Figures 6(b) and 6(c)), SMC was arranged in disorder with irregular nucleus, the chromatin was massive with dark staining, many large cytoplasm lysis vacuoles were distributed intracellularly, dense bodies and myofilaments were decreased, and there was swelling in the mitochondria as well as vacuolar degeneration and dissolution.
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