dendritic spine


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dendritic spine

n.
Any of various outgrowths of certain nerve-cell dendrites, ranging in shape from small knobs to thornlike or filamentous processes, that are preferential sites of synaptic axodendritic contact.
References in periodicals archive ?
Single spine stimulation by two-photon activation (uncaging) of glutamate has revealed that the uncaging-evoked AMPA-R current through the stimulated spine is strongly correlated with spine head size, which supports the hypothesis that dendritic spine size is a key determinant of synaptic efficacy.
Alot et al., "Influence of matrix metalloproteinase MMP-9 on dendritic spine morphology," Journal of Cell Science, vol.
(54,58-60) Cocaine increased dendritic spine density and dendritic branches in the NAc shell, medium spiny neurons, mPFC pyramidal neurons, and VTA dopaminergic neurons (Table 3).
For proteins, significant gene ontologies were dendritic spine morphogenesis and the nitric oxide biosynthetic process with dendritic spine morphogenesis being highly significant.
Dopamine depletion of the prefrontal cortex induces dendritic spine loss: reversal by atypical antipsychotic drug treatment.
Morris water maze test was evaluated; immunofluorescent histochemistry was used to identify astrocytes activation, and immunofluorescent dendritic spine analysis was used to identify the dendritic spines morphological characteristics expression levels in hippocampus.
An early computational model of calcium influx, diffusion, and buffering in a single cortical dendritic spine compared the calcium amplitudes occurring in response to differing stimulation frequencies (Gamble and Koch, 1987).
Receptors [GABA.sub.A] are found on dendritic spine heads and necks [5].
Receptors on the postsynaptic neuron located on the dendritic spine of the synapse bind the neurotransmitters, causing local depolarization of the membrane at these junctions.
Reduction of Dendritic Spine Density in Diabetic Rat.