dendritic spine


Also found in: Wikipedia.

dendritic spine

n.
Any of various outgrowths of certain nerve-cell dendrites, ranging in shape from small knobs to thornlike or filamentous processes, that are preferential sites of synaptic axodendritic contact.
References in periodicals archive ?
54,58-60) Cocaine increased dendritic spine density and dendritic branches in the NAc shell, medium spiny neurons, mPFC pyramidal neurons, and VTA dopaminergic neurons (Table 3).
For proteins, significant gene ontologies were dendritic spine morphogenesis and the nitric oxide biosynthetic process with dendritic spine morphogenesis being highly significant.
Dopamine depletion of the prefrontal cortex induces dendritic spine loss: reversal by atypical antipsychotic drug treatment.
Morris water maze test was evaluated; immunofluorescent histochemistry was used to identify astrocytes activation, and immunofluorescent dendritic spine analysis was used to identify the dendritic spines morphological characteristics expression levels in hippocampus.
An early computational model of calcium influx, diffusion, and buffering in a single cortical dendritic spine compared the calcium amplitudes occurring in response to differing stimulation frequencies (Gamble and Koch, 1987).
Receptors on the postsynaptic neuron located on the dendritic spine of the synapse bind the neurotransmitters, causing local depolarization of the membrane at these junctions.
The study has begun to investigate the effects of dendritic spine changes in the sensory and motor systems after SCI/D, which could help identify ways to therapeutically target pain and spasticity.
mGluR5 knockout mice display increased dendritic spine densities.
One target gene of CREB encodes a molecule, brain-derived neurotrophic factor (BDNF), which plays an important role in the regulation of synaptic plasticity and dendritic spine structure (Minichiello 2009; Poo 2001; Tao et al.
An activity-induced microRNA controls dendritic spine formation by regulating Racl-PAK signaling.
A dendritic spine is a small membranous protrusion from a neuron's dendrite that typically receives input form a single synapse of an axon, stores synaptic strength, and helps transmit electrical signals to the neuron's cell body.