demyelinization


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demyelination

 [de-mi´ĕ-lin-a´shun]
destruction, removal, or loss of the myelin sheath of a nerve or nerves. Called also demyelinization and myelinolysis.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

de·my·e·li·na·tion

, demyelinization (dē-mī'e-lin-ā'shŭn, dē-mī'ĕ-lin-i-za'shŭn),
Loss of myelin with preservation of the axons or fiber tracts. Central demyelination occurs within the central nervous system (for example, the demyelination seen with multiple sclerosis); peripheral demyelination affects the peripheral nervous system (for example, the demyelination seen with Guillain-Barré syndrome).
Farlex Partner Medical Dictionary © Farlex 2012

de·my·e·li·na·tion

, demyelinization (dē-mī'e-lin-ā'shŭn, -ī-zā'shŭn)
Loss of myelin with preservation of the axons or fiber tracts. Central demyelination occurs within the central nervous system (e.g., the demyelination seen with multiple sclerosis); peripheral demyelination affects the peripheral nervous system (e.g., the demyelination seen with Guillain-Barré syndrome).
Medical Dictionary for the Health Professions and Nursing © Farlex 2012

de·my·e·li·na·tion

, demyelinization (dē-mī'e-lin-ā'shŭn, -ī-zā'shŭn, dē-mīĕ-li-nāshŭn, -lin-ī-zāshŭn)
Loss of myelin with preservation of the axons or fiber tracts.
Medical Dictionary for the Dental Professions © Farlex 2012
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Demyelinization can slow or even block the flow of signals between the CNS and the rest of the body.
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Also, LPS-induced spinal cord damage shows significant demyelinization associated with an important reduction in the amount of oligodendrocytes [102].
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Minden and Schiffer (1991) reported that depressive episodes can precede the onset of other MS symptoms and may be considered an early sign of the demyelinization that occurs during an MS exacerbation.
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Histologic multifocal areas of inflammation and demyelinization are Ibund.
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Demyelinization and optic neuritis can occur with etanercept, but the absolute incidence is still low, estimated at between 2 and 6 per 100,000 treated patients.
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However, these explanations do not account for the severe nerve damage, demyelinization, kidney insufficiency, and anemia observed in lead-exposed subjects [2, 9-11].
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The virus can invade the central nervous system and, in some cases, cause acute or subacute encephalitis sometimes associated with diffuse or multifocal demyelinization (9).
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Multiple sclerosis (MS) is a chronic, often progressive, degenerative, inflammatory, neurological immune disease, characterized by demyelinization of axons.
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