There is too little information on the early histologic changes of acute demyelinating optic neuritis
as a manifestation of multiple sclerosis or neuromyelitis optica for definitive guidance in the differential diagnosis of ION.
Ko, "Should oral corticosteroids be used to treat demyelinating optic neuritis
?," Journal of Neuro-Ophthalmology, vol.
Idiopathic demyelinating optic neuritis
(IDON) is a demyelinating autoimmune disease of optic nerve, characterized by acute vision loss.
The patients who had acute demyelinating optic neuritis
were treated with intravenous methylprednisolone 30 mg/kg/day for 3 days followed by 11 days of oral prednisolone 1 mg/kg/day for 11 days as per the Optic Neuritis Treatment Protocol.
Acute demyelinating optic neuritis
. Curr opin ophthalmol.
In most parts of the world acute demyelinating optic neuritis
(ON) is the most common cause of unilateral painful visual loss in a young adult.
First described in 1883, optic perineuritis is an uncommon orbital inflammatory diseaseinvolving theoptic nervesheath; although it tends to mimic demyelinating optic neuritis
, there are some clinical features that help to distinguish the two .
The most common form of optic neuritis is acute demyelinating optic neuritis
. The annual incidence of optic neuritis, as estimated in population-based studies, is approximately 3-5 per 100,000 per year.
The clinical diagnosis of acute demyelinating optic neuritis
is based on medical history and clinical features (106), so when faced with a patient with idiopathic demyelinating optic neuritis
, ophthalmologists should consider the following: