demyelinating encephalopathy

de·my·e·li·nat·ing en·ceph·a·lop·a·thy

extensive idiopathic loss of myelin sheaths in the brain, as occurs in leukodystrophy.
Farlex Partner Medical Dictionary © Farlex 2012
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For example, all findings of the patient in case 1 in the early stage, such as first complaint with fever and headache, the negative results of CSF, diffuse infiltrative leukoencephalopathy on MRIs, and the history of infection supported the diagnosis of inflammatory demyelinating encephalopathy rather than lymphoma.[sup]1 H-MRS may be helpful for discriminating PCNSL with atypical MR imaging features from tumefactive demyelinating lesions (TDLs).