demyelinating diseases


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demyelinating diseases

Diseases that feature loss of the myelin sheath of nerve fibres in the white matter of the central nervous system. The most important of the demyelinating diseases is MULTIPLE SCLEROSIS. Others include acute demyelinating encephalomyelitis, which may follow measles or chickenpox, and neuromyelitis optica, in which both optic nerves are affected as well as the spinal cord.
References in periodicals archive ?
Neuromyelitis optica: a distinct demyelinating disease of the central nervous system.
In the study conducted by Tandon et al., P100 latency was prolonged in hypertensives and suggested that hypertensive milieu affects neuronal excitation/conduction in the visual pathway.[2] In the study conducted by Marsh et al., P100 latency of visual evoked response was delayed in pre-eclamptic women.[8] There was a delayed conduction in brainstem auditory evoked response in Grade III hypertension.[9] There was impairment in sensory conduction in human beings in hypertension.[10] P100 latency was prolonged in patients with demyelinating disease like multiple sclerosis.[11] There is a significant change in VEP with normal fluctuation in carotid pressure and heart rate.[12] These findings were similar to the results of the present study.
As some authors have suggested, we believe that it would be adeguate to carry out a periodic assessment of the presence of signs and symptoms of a demyelinating disease, both at a central and a peripheral level, in patients who receive this type of drugs (6).
Environmental and genetic factors in pediatric inflammatory demyelinating diseases. Neurology.
Infertility and reproductive problems have been reported in women with multiple sclerosis (MS), a demyelinating disease. MS is one of the most important demyelinating diseases.
Under suspicion of tumefactive multiple sclerosis and other demyelinating diseases, intravenous steroid pulse (methylprednisolone 1 g) therapy for five days and subsequent high-dose prednisolone was administered.
(9) examined 84 IBD patients with neurological manifestations in their review published in 2010 and reported neuromuscular diseases with inflammatory and axonal neuropathies, arterial or venous cerebrovascular diseases and demyelinating diseases.
Demyelinating diseases can affect the swallowing mechanism because of involvement of the brainstem, various cranial nerves, several regions of the cerebral cortex, and cerebellum.
In addition, being able to generate large numbers of patient-specific oligodendrocytes will support both cell transplantation therapeutics for demyelinating diseases and the identification of new classes of drugs to treat such disorders," said Lee Rubin of the Harvard Stem Cell Institute.