demyelinate

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demyelinate

(dē-mī′ə-lə-nāt′)
tr.v. demyelin·ated, demyelin·ating, demyelin·ates
To destroy or remove the myelin sheath of (a nerve fiber), as through disease.

de·my′e·lin·a′tion n.
References in periodicals archive ?
Autoimmune diseases are on the rise, and chronic inflammatory demyelinating polyneuropathy (CIDP) is no exception.
A randomized trial of plasma exchange in acute inflammatory central nervous system inflammatory demyelinating diseases.
Comparison of electrophysiological findings in axonal and demyelinating Guillain-Barre syndrome.
In conclusion, hearing loss might be a feature of demyelinating disorders.
Acute Demyelinating Events Following Vaccines: A Case-Centered Analysis.
To date, the reason for the demyelinating effect of anti-TNF [alpha] drugs remains unclear.
Environmental and genetic factors in pediatric inflammatory demyelinating diseases.
This is in accordance with biopsy findings in MOG antibody patients with acute demyelinating episodes, which reveal a lesion pattern similar to MS pattern II with demyelination and complement activation [9, 30-33].
Given that the situation was not hyperacute, the symptoms were better explained by the inflammatory and demyelinating reaction within the spinal cord rather than direct contact with the foreign body.
Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) with hypertrophic spinal radiculopathy mimicking neurofibromatosis.
An autoantibody against anti-melanoma differentiation-associated gene 5 (anti-MDA5) is capable of recognizing long dsRNA structures or binding to viral RNA and contributes to type 1 interferon-mediated inflammation.[1] The anti-MDA5 is identified from the group of clinically amyopathic dermatomyositis initially and associated with rapidly progressive interstitial lung disease (ILD).[2] Here, we described the patient with anti-MDA5-positive dermatomyositis whose initial presentation mimicking demyelinating polyneuropathy.
Diagnosis of a concurrent polyneuropathy in this case was presumably attributed to the electrodiagnostic testing, which showed a "mixed axonal demyelinating polyneuropathy." Given that the polyneuropathy attributed to cobalamin deficiency is classically an axonal polyneuropathy, we take great interest in the report of a primary demyelinating component to this patient's polyneuropathy.