demethylation


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de·meth·yl·a·tion

(dē-meth'i-lā'shŭn),
The enzymatic removal of methyl groups.
Farlex Partner Medical Dictionary © Farlex 2012
References in periodicals archive ?
The absence of MDIPU and presence of DDIPU suggests either rapid demethylation of MDIPU to DDIPU in the soil or a greater retention of MDIPU by the soil.
To ensure the likelihood of a positive ROI, farmers should focus on applications at VT and use fungicides that include a mix of demethylation inhibitor and quinone outside inhibitor active ingredients.
Histone demethylation mediated by the nuclear amine oxidase homolog LSD1.
The latest study describes the demethylation process of Hg in marine fish (black seabream) after Se treatment.
The findings revealed that treatment with 10 [micro]M 5-Aza-CdR for 4 days induced partial demethylation of RASSF1A gene in PANC-1 cell line.
These cells express the pluripotency-associated markers OCT3/4, LIN28A, and NANOG histologically and begin a process of global DNA demethylation necessary for the later establishment of sex-specific gametic imprinting [21-23].
rapa populations, the 5-azaC demethylation treatment altered plant size, and this change in size was heritable, but they did not examine life history changes or environmental interactions.
Another similar study performed on DNA demethylation with 5-azaC showed increased miR-203 expression [33].
[33] demonstrated that the antipsychotic drugs clozapine and sulpiride increased the cortical and striatal demethylation of hypermethylated RELN and GAD1 promoters in the prefrontal cortex of mice after 7d of methionine treatment.
An Epigenetics Screening Library was purchased from Cayman Chemical (Ann Arbor, MI) and consists of 148 small-molecule compounds that are involved in different epigenetic modifications such as DNA/histone methylation and demethylation as well as histone acetylation and deacetylation.
In a growing human hair, Hcykeratin levels increase along the hair shaft as a result of copper and iron-dependent demethylation of methionine residues of keratin [18].