delta F-508

delta F-508

The most common mutation in the cystic fibrosis (CF) gene (the CFTR gene). It is responsible for 70% of all cases of CF.
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References in periodicals archive ?
Available Delta F-508 mutation analyses were noted.
Gene analysis for Delta F-508 was identified in 12 (27.90%) patients.
Most commonly reported CF related genetic mutation among Caucasians is Delta F-508.6 Limited range of genetic mutation analysis is available in our part of world.
Around a decade ago, Delta F-508 mutation analysis was started at Aga Khan University Hospital molecular laboratory on the basis of reported genetic mutations in CF Children from our adjoining region.7,8 All patients with positive sweat chloride were analyzed for Delta F-508 genetic mutation.
In our study, 12 (27.90%) patients have shown positive results for Delta F-508 genetic mutation with 5 (11.62%) were heterozygous and 7 (16.27%) were homozygous.