delayed transfusion reaction

delayed transfusion reaction

The immune-mediated destruction of donated blood cells, occurring about 3 to 5 days after a transfusion and often resulting from recipient antibodies against minor antigens on donor red cells. Delayed transfusion reactions are relatively uncommon except in patients who have received many previous transfusions and have become alloimmunized (e.g., patients with sickle cell anemia). A sudden drop in hemoglobin and hematocrit levels is a hallmark.
References in periodicals archive ?
Antigen-negative units may be selected to prevent a delayed transfusion reaction.
8,9) delayed transfusion reactions were noted and managed appropriately.
There is also a newly identified urgency to better educate both professionals and the community about the need to have a greater diversity among donors, in order to prevent delayed transfusion reactions, which is at highest risk when a patient of African ancestry receives blood from a donor of European ancestry.

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