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delavirdine/del·a·vir·dine/ (del″ah-vir´dēn) an antiretroviral, inhibiting reverse transcriptase; used as the mesylate salt in the treatment of HIV infection.
An antiviral drug, C22H28N6O3S, that is a non-nucleoside reverse transcriptase inhibitor and is used in its mesylate form in combination with other drugs for the treatment of HIV infection.
a nonnucleoside reverse transcriptase inhibitor.
indications It is used to treat HIV-1 in combination with zidovudine or didanosine.
contraindications Known hypersensitivity to this drug or to atevirdine prohibits its use.
adverse effects Life-threatening effects are hepatotoxicity, neutropenia, leukopenia, thrombocytopenia, anemia, granulocytopenia, and nephrotoxicity. Other adverse effects include diarrhea, abdominal pain, nausea, fatigue, headache, rash, pain, myalgia, vomiting, and dyspepsia.