IgE can cause mast cell degranulation, and IgG 1 can cause polymorphonuclear cells to become activated and degranulate
The interaction term induces a transition probability between the unperturbed states of the basophils and the state where they will degranulate
When the skin or mucous membranes are reexposed to the allergen(s), IgE bound to the receptors on the surface of the aforementioned cells causes them to degranulate
and release histamine, pros-taglandin, leukotrienes, etc.
As a result of allergic sensitization, mast cells degranulate
and release various biological mediators in allergen-specific IgE-mediated AD (Amin, 2012).
Diesel exhaust particles directly induce activated mast cells to degranulate
and increase histamine levels and symptom severity.
ADP, secreted from dense granules induces other platelets to degranulate
and potentiate coagulation.
When a person comes in frequent contact with a certain antigen or antigens to which the body has formed immunoglobulin (IgE) antibodies, antigen-antibody reactions occur along the surface of mast cells, causing the cells to degranulate
It seems in this case, that although massively increased in number as shown on the bone marrow biopsy, her mast cells were remarkably stable and not triggered to degranulate
by any of the usual factors.
During repair platelets become entrapped in a fibrin clot and degranulate
releasing two primary growth factors: PDGF and TGF-B.
The neutrophils then degranulate
and secrete prostaglandin metabolites that contribute to more endothelial damage, which leads to thrombosis, ischemia, and necrosis.
white blood cell) into tissues, where they can degranulate
Immunoglobulin E binding to mast cells "sensitizes" the mast cells to degranulate
when multivalent antigens cross-link Fc[Epsilon]R-bound IgE (Figure).