Degas

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simethicone

(si-meth-i-kone) ,

Degas

(trade name),

Extra Strength Gas-X

(trade name),

Flatulex

(trade name),

Gas Relief

(trade name),

Gas-X

(trade name),

Genasyme

(trade name),

Infacol

(trade name),

Maximum Strength Mylanta Gas

(trade name),

Mylanta Gas

(trade name),

Mylicon

(trade name),

Ovol

(trade name),

Pediacol

(trade name),

Phazyme

(trade name)

Classification

Therapeutic: antiflatulent
Pregnancy Category: UK

Indications

Relief of painful symptoms of excess gas in the GI tract that may occur postoperatively or as a consequence of:
  • Air swallowing,
  • Dyspepsia,
  • Peptic ulcer,
  • Diverticulitis.

Action

Causes the coalescence of gas bubbles.
Does not prevent the formation of gas.

Therapeutic effects

Passage of gas through the GI tract by belching or passing flatus.

Pharmacokinetics

Absorption: No systemic absorption occurs.
Distribution: Not systemically distributed.
Metabolism and Excretion: Excreted unchanged in the feces.
Half-life: Unknown.

Time/action profile (antiflatulent effect)

ROUTEONSETPEAKDURATION
POimmediateunknown3 hr

Contraindications/Precautions

Contraindicated in: Not recommended for infant colic.
Use Cautiously in: Abdominal pain of unknown cause, especially when accompanied by fever; Obstetric / Lactation: Has been used safely.

Adverse Reactions/Side Effects

None significant.

Interactions

Drug-Drug interaction

None significant.

Route/Dosage

Oral (Adults) 40–125 mg qid, after meals and at bedtime (up to 500 mg/day).
Oral (Children 2–12 yr) 40 mg 4 times daily.
Oral (Children <2 yr) 20 mg 4 times daily (up to 240 mg/day).

Availability (generic available)

Chewable tablets: 40 mgOTC, 80 mgOTC, 125 mgOTC, 150 mgOTC
Tablets: 60 mgOTC, 80 mgOTC, 95 mgOTC
Capsules: 125 mgOTC, 166 mgOTC, 180 mgOTC
Drops: 40 mg/0.6 mLOTC, 40 mg/mLOTC, 95 mg/1.425 mLOTC
In combination with: antacidsOTC. See combination drugs.

Nursing implications

Nursing assessment

  • Assess patient for abdominal pain, distention, and bowel sounds prior to and periodically throughout course of therapy. Frequency of belching and passage of flatus should also be assessed.

Potential Nursing Diagnoses

Acute pain (Indications)

Implementation

  • Oral: Administer after meals and at bedtime for best results. Shake liquid preparations well prior to administration. Chewable tablets should be chewed thoroughly before swallowing for faster and more complete results.
    • Drops can be mixed with 30 mL of cool water, infant formula, or other liquid as directed. Shake well before using.

Patient/Family Teaching

  • Explain to patient the importance of diet and exercise in the prevention of gas. Also explain that this medication does not prevent the formation of gas.
  • Advise patient to notify health care professional if symptoms are persistent.

Evaluation/Desired Outcomes

  • Decrease in abdominal distention and discomfort.

Degas

To release and vent gases. New building materials often give off gases and odors and the air should be well circulated to remove them.
References in periodicals archive ?
Typically, the best solution for dealing with porosity is to reduce hydrogen and oxides prior to casting via a treatment combining automated cleaning flux addition with rotary impellor degassing.
Our experiments showed that a plate sonotrode gave a continuous degassing efficiency of at least 50 per cent in the melt flow rising to 75 per cent in batch operation.
Having proved that ultrasound degassing of molten aluminium alloys is cleaner, greener and cheaper than current methods, our team of scientists and engineers from Brunei University is working within a European consortium to take the breakthrough a step further, achieving a continuous process that would allow us to apply degassing to much larger melt volumes and upstream from the casting mould.
Consumption of aluminium should be sufficient for ensuring removal of excessive oxidation (difference between really measured oxidation and minimal amount of oxygen, necessary for decarburization) in the semi-finished product, and at the same time it should not prevent reaction process of vacuum-oxygen decarburization of the metal in degassing (Figure 2).
Despite the effectiveness of helium as a degassing agent, though, some researchers shy away from using it because it can prove expensive, and the stocking of unwieldy canisters can be a hassle.
Tests show MAG degassing rate constants nearly identical to traditional compressed air sparging.
Vacuum degassing causes hydrogen to diffuse and separate from the liquid
Project Management and Quality Assurance and Quality Control tasks are being performed on a number of well heads, flowlines, and degassing Stations as wells as technical office functions such as project planning, and administritive functions in order to support the client with the rehabilitation and development of the oil field.
Thinky mixing and degassing has been found valuable for high viscosities, for materials with highly different densities, or for mixing dry particles into liquids.
Flexis Air One-way coffee valves can be applied using automatic label application systems at speeds nearly twice that of injection molded heat seal-applied degassing valves.
Lances Precast offers two new designs of nitrogen/ argon delivery tubes for the removal of hydrogen gas from molten aluminum--degassing "T" and degassing "lance.