deep sequencing


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deep sequencing

Examination of a nucleic acid genome with such precision that even very rare genetic mutations are identified.
See also: sequencing
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Deep sequencing can be performed on any of a number of different platforms.
In the deep sequencing study, the amplified NS3, NS5A, and NS5B fragments were modified by the Multiplexing Sample Preparation Kit (Illumina, San Diego, CA, USA), and sequence analysis was performed by Illumina Hiseq 2000.
Snp discovery and allele frequency estimation by deep sequencing of reduced representation libraries.
The Interlaboratory Robustness of Next-Generation Sequencing (IRON) study: a deep sequencing investigation of TET2, CBL and KRAS mutations by an international consortium involving 10 laboratories.
She also wrote that the model allowed her team to examine HIV antibodies that were induced by vaccination was not seen in other animal models and that it highlighted the various challenges of evaluating studies related to immunisation with deep sequencing of the antibody variable regions.
Recently we carried out a deep sequencing applied to sea urchin Strongylocentrotus nudus in a small RNA library isolated from male and female gonad and found 36 miRNAs significantly varied between control and ZnSO4 stressed samples (Wei et al.
Study author Jie Qiao of Third Hospital, Peking University said that the deep sequencing analysis avoids two types of genetic problems and will be able to double the success rate of test tube baby technology from 30 percent to 60 percent, or even more.
Its services include specialization in developing RNA, DNA and IHC-based assays for biomarker research in oncology drug development and research in deep sequencing of single gene mutations from its CLIA-certified headquarters.
Services include deep sequencing, microarrays and qRT- PCR.
Next-generation deep sequencing reveals that the rate of HIV superinfection is the same as HIV incidence in heterosexuals in Africa.
X-BODY said that its deep sequencing hit analysis identifies and characterises rare antibodies with the desired therapeutic properties.
The researchers used advanced deep sequencing and developed bioinformatics technologies to analyze all the small RNA molecules that are transcribed from all the genes in the pig genome.